Title:
EXTERNAL PREPARATION
Document Type and Number:
WIPO Patent Application WO/2020/241605
Kind Code:
A1
Abstract:
To provide a nonaqueous external preparation comprising dexmedetomidine in which the crystallization of dexmedetomidine in the preparation is suppressed and which has excellent percutaneous absorbability. A nonaqueous external preparation that comprises: (A) dexmedetomidine or a salt thereof; (B) an aliphatic alcohol having 10-12 carbon atoms; (C) a propylene glycol mono-ester of a fatty acid having 6-16 carbon atoms; (D) an organic acid; and (E) an organic acid salt.
Inventors:
UCHITOMI RYO (JP)
YAMAZAKI YUHIRO (JP)
YAMAZAKI YUHIRO (JP)
Application Number:
PCT/JP2020/020642
Publication Date:
December 03, 2020
Filing Date:
May 26, 2020
Export Citation:
Assignee:
KYUKYU YAKUHIN KOGYO KK (JP)
MARUISHI PHARMA (JP)
MARUISHI PHARMA (JP)
International Classes:
A61K31/4174; A61K9/06; A61K9/70; A61K47/10; A61K47/12; A61K47/14; A61P25/20
Domestic Patent References:
| WO2015093503A1 | 2015-06-25 | |||
| WO2015093503A1 | 2015-06-25 |
Foreign References:
| JP2016532642A | 2016-10-20 | |||
| JPH05503916A | 1993-06-24 |
Other References:
See also references of EP 3977992A4
Attorney, Agent or Firm:
THE PATENT CORPORATE BODY ARUGA PATENT OFFICE (JP)
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