FERRITIN HEAVY CHAIN SUBUNIT-BASED DRUG CARRIER - KUNSHAN XINYUNDA BIOTECH CO LTD

Title:

FERRITIN HEAVY CHAIN SUBUNIT-BASED DRUG CARRIER

Document Type and Number:

WIPO Patent Application WO/2021/008454

Kind Code:

A1

Abstract:

The present application relates to the technical field of biological medicine. In particular, the present application relates to a ferritin heavy chain subunit-based drug carrier. More specifically, the present application relates to a mutant polypeptide of a ferritin heavy chain subunit, a fusion protein containing the polypeptide, a cage-like protein containing the polypeptide, and an application thereof as a drug carrier.

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Inventors:

KE TIANYI (CN)
LAO FANG (CN)
YAO DEHUI (CN)
OUYANG FANGXING (CN)
JIANG BING (CN)
LI YANLIANG (CN)
WEN BAIGANG (CN)
CHENG JIANWEI (CN)
YAN XICHONG (CN)
LIU YAN (CN)
LI FAN (CN)
LI BO (CN)
ZHANG RONGKUN (CN)
FU YE (CN)
XU JUFANG (CN)

Application Number:

PCT/CN2020/101312

Publication Date:

January 21, 2021

Filing Date:

July 10, 2020

Export Citation:

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Assignee:

KUNSHAN XINYUNDA BIOTECH CO LTD (CN)

International Classes:

A61K38/17; C07K14/47; A61K51/08; C07K19/00; C12N15/62

Domestic Patent References:

WO2019087155A1	2019-05-09
WO2019087155A1	2019-05-09
WO2008048288A2	2008-04-24

Foreign References:

CN106922149A	2017-07-04
CN106922149A	2017-07-04
CN108503704A	2018-09-07
CN108503704A	2018-09-07

Other References:

YANG, CAIYUN ET AL.: "The Surface Modification of Ferritin and Its Applications", PROGRESS IN CHEMISTRY, vol. 28, no. 1,, 25 January 2016 (2016-01-25), DOI: 20200915111231Y
GENPEPT: "6B8F_A", 17 May 2018 (2018-05-17), DOI: 20200915113200X
GENPEPT: "2CN7_A", 9 May 2019 (2019-05-09), DOI: 20200915112541X
GOZZELINO, R. ET AL.: "Coupling Heme and Iron Metabolism via Ferritin H Chain", ANTIOXIDANTS & REDOX SIGNALING, vol. 20, no. 11,, 31 December 2014 (2014-12-31), XP055774012, DOI: 20200915112208Y

Attorney, Agent or Firm:

NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD (CN)

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