Title:
FORMULATION CONTAINING (LYSO-) PHOSPHATIDYLSERINE FOR THE PREVENTION AND TREATMENT OF STRESS STATES IN WARM-BLOODED ANIMALS
Document Type and Number:
WIPO Patent Application WO/2003/013549
Kind Code:
A2
Abstract:
The invention relates to a formulation containing phosphatidylserine (PS) and/or lyso-phosphatidylserine for the prevention and treatment of mental and physical stress states. The phosphatidylserine is combined inter alia with vegetable extracts. According to the invention, daily doses range from 50 -1000 mg PS, administered over a maximum period of six months. Preferred subjects are human beings of 10-50 years of age.
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Inventors:
JAEGER RALF (DE)
BOEKENKAMP DIRK (DE)
BOEKENKAMP DIRK (DE)
Application Number:
PCT/EP2002/008940
Publication Date:
February 20, 2003
Filing Date:
August 09, 2002
Export Citation:
Assignee:
DEGUSSA BIOACTIVES GMBH & CO K (DE)
JAEGER RALF (DE)
BOEKENKAMP DIRK (DE)
JAEGER RALF (DE)
BOEKENKAMP DIRK (DE)
International Classes:
A23L1/30; A61K31/685; A61K36/00; A61K36/38; A61K36/48; A61K36/67; A61K36/8962; A61K45/00; A61K47/04; A61K47/12; A61K47/26; A61P5/46; A61P9/12; A61P25/00; A61P25/02; A61P25/22; A61P43/00; (IPC1-7): A61K31/66; A61K35/78; A61K31/185; A61K31/195; A61K31/205; A61K31/40; A61P25/22; A23L1/30
Domestic Patent References:
| WO1998004253A1 | 1998-02-05 | |||
| WO1999037155A1 | 1999-07-29 | |||
| WO2001084961A2 | 2001-11-15 | |||
| WO2001026646A1 | 2001-04-19 | |||
| WO2001003325A2 | 2001-01-11 |
Foreign References:
| EP0711559A2 | 1996-05-15 | |||
| EP0148045A1 | 1985-07-10 | |||
| FR2775600A1 | 1999-09-10 |
Other References:
PATENT ABSTRACTS OF JAPAN vol. 015, no. 027 (C-0797), 22. Januar 1991 (1991-01-22) & JP 02 265457 A (NIKKEN FOOD KK), 30. Oktober 1990 (1990-10-30)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1995-063782 XP002222606 & JP 03 011827 A (KATSUNARI S.K.K.), 21. Februar 2000 (2000-02-21)
MONTELEONE P. ET AL.: "Blunting by chronic phosphatidylserine administration of stress-induced activation of the hypothalamic-pituitary-adrenal axis in healthy men." EUR. J. CLIN. PHARMACOL., Bd. 42, Nr. 4, 1992, Seiten 385-388, XP001119805
BENTON D. ET AL.: "The influence of phosphatidylserine supplementation on mood and heart rate when faced with an acute stressor." NUTR. NEUROSCIENCE., Bd. 4, 2001, Seiten 169-178, XP001119807
DATABASE WPI Derwent Publications Ltd., London, GB; AN 2000-106919 XP002222607 & CN 1 232 649 A (UNIV. SHENYANG), 27. Oktober 1999 (1999-10-27)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1996-237622 XP002222608 & RU 2 045 275 A (A MED. TOMSK PHARMACOL. RES. INST.), 10. Oktober 1995 (1995-10-10)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1999-444320 XP002222609 & WO 99 36080 A (REXALL SUNDOWN INC.), 22. Juli 1999 (1999-07-22)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1997-539684 XP002222610 & JP 09 227394 A (TAISHO PHARM. CO.), 2. September 1997 (1997-09-02)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1995-212887 XP002222611 & JP 07 126179 A (NISSHING FLOUR MILLING CO.), 16. Mai 1995 (1995-05-16)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1995-063782 XP002222606 & JP 03 011827 A (KATSUNARI S.K.K.), 21. Februar 2000 (2000-02-21)
MONTELEONE P. ET AL.: "Blunting by chronic phosphatidylserine administration of stress-induced activation of the hypothalamic-pituitary-adrenal axis in healthy men." EUR. J. CLIN. PHARMACOL., Bd. 42, Nr. 4, 1992, Seiten 385-388, XP001119805
BENTON D. ET AL.: "The influence of phosphatidylserine supplementation on mood and heart rate when faced with an acute stressor." NUTR. NEUROSCIENCE., Bd. 4, 2001, Seiten 169-178, XP001119807
DATABASE WPI Derwent Publications Ltd., London, GB; AN 2000-106919 XP002222607 & CN 1 232 649 A (UNIV. SHENYANG), 27. Oktober 1999 (1999-10-27)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1996-237622 XP002222608 & RU 2 045 275 A (A MED. TOMSK PHARMACOL. RES. INST.), 10. Oktober 1995 (1995-10-10)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1999-444320 XP002222609 & WO 99 36080 A (REXALL SUNDOWN INC.), 22. Juli 1999 (1999-07-22)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1997-539684 XP002222610 & JP 09 227394 A (TAISHO PHARM. CO.), 2. September 1997 (1997-09-02)
DATABASE WPI Derwent Publications Ltd., London, GB; AN 1995-212887 XP002222611 & JP 07 126179 A (NISSHING FLOUR MILLING CO.), 16. Mai 1995 (1995-05-16)
Attorney, Agent or Firm:
WEICKMANN & WEICKMANN (München, DE)
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