Title:
FUSED HETEROCYCLIC DERIVATIVE
Document Type and Number:
WIPO Patent Application WO/2013/039140
Kind Code:
A1
Abstract:
The present invention pertains to a compound or a pharmacologically acceptable salt thereof, which has an excellent diglyceride acyltransferase (DGAT) inhibitory effect and an anorectic effect. The compound or pharmacologically acceptable salt thereof is represented by general formula (I) [in the formula, R1 is a hydrogen atom or a carboxy group; R2 and R3 represent, independently, a C1 to C6 alkyl group, or R2 and R3 bond together as carbon atoms, forming a C3 to C6 cycloalkane, wherein one group may be substituted by a carboxy group or a carboxymethyl group; U is a nitrogen atom or the like; V is a nitrogen atom or the like; W is a nitrogen atom or the like; Z is a nitrogen atom or the like; R4 is a halogen atom or a C1 to C6 alkyl group; A is an oxygen atom or the like; E is a nitrogen atom or the like; J is a nitrogen atom or the like; L is a nitrogen atom or the like; M is a nitrogen atom or the like; m is an integer of 0 or 1; and n is an integer from 0 to 2].
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Inventors:
UTO YOSHIKAZU
UENO YUKO
SUZUKI KEIKO
MORI YUTAKA
UENO YUKO
SUZUKI KEIKO
MORI YUTAKA
Application Number:
PCT/JP2012/073442
Publication Date:
March 21, 2013
Filing Date:
September 13, 2012
Export Citation:
Assignee:
DAIICHI SANKYO CO LTD (JP)
UTO YOSHIKAZU
UENO YUKO
SUZUKI KEIKO
MORI YUTAKA
UTO YOSHIKAZU
UENO YUKO
SUZUKI KEIKO
MORI YUTAKA
International Classes:
C07D263/58; A61K31/423; A61K31/4439; A61K31/444; A61K31/497; A61K31/506; A61P1/16; A61P3/04; A61P3/06; A61P3/10; A61P9/10; A61P13/12; A61P25/00; A61P27/02; A61P27/12; A61P43/00; C07D403/12; C07D413/12; C07D417/12; C07D498/04
Foreign References:
| JP2008255024A | 2008-10-23 | |||
| JP2007502862A | 2007-02-15 | |||
| JP2009536629A | 2009-10-15 |
Attorney, Agent or Firm:
ISHIBASHI Koki et al. (JP)
Kimiki Ishibashi (JP)
Kimiki Ishibashi (JP)
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Claims: