Title:
FUSED TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/041643
Kind Code:
A1
Abstract:
The present disclosure relates to a fused tricyclic compound, a preparation method therefor, and medical use thereof. Specifically, the present disclosure relates to a fused tricyclic compound represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and use thereof as a therapeutic agent, and particularly, to use thereof as a PARP1 inhibitor and use thereof in the preparation of a medicament for treating and/or preventing cancer.
Inventors:
LI XIN (CN)
SHEN FENG (CN)
DONG HUAIDE (CN)
HE FENG (CN)
SHEN FENG (CN)
DONG HUAIDE (CN)
HE FENG (CN)
Application Number:
PCT/CN2023/114986
Publication Date:
February 29, 2024
Filing Date:
August 25, 2023
Export Citation:
Assignee:
JIANGSU HENGRUI PHARMACEUTICALS CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
SHANGHAI HENGRUI PHARMACEUTICAL CO LTD (CN)
International Classes:
C07D471/14; A61K31/4985; A61P35/00; A61P35/02; C07D519/00
Domestic Patent References:
| WO2022247816A1 | 2022-12-01 | |||
| WO2022028389A1 | 2022-02-10 |
Foreign References:
| CN114144413A | 2022-03-04 |
Attorney, Agent or Firm:
GE CHENG & CO., LTD. (CN)
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