FUSION PROTEIN CAPABLE OF SELF-ASSEMBLY BY COMPRISING PURIFICATION TAG AND Α-HELIX TAG, AND METHOD FOR PURIFYING RECOMBINANT PROTEIN BY USING SAME

Title:

FUSION PROTEIN CAPABLE OF SELF-ASSEMBLY BY COMPRISING PURIFICATION TAG AND Α-HELIX TAG, AND METHOD FOR PURIFYING RECOMBINANT PROTEIN BY USING SAME

Document Type and Number:

WIPO Patent Application WO/2024/071956

Kind Code:

A1

Abstract:

The present invention relates to a fusion polypeptide and a method for purifying a target protein by using same, the polypeptide having any one from among a His tag, a HAT tag and an HQ tag, and an α-helix peptide tag of which the major amino acids are charged and hydrophobic amino acids. Since the fusion polypeptide has an ability to induce self-assembly by being fused with the target protein, the target protein purification method using same enables the isolation and purification of the target protein merely through very simple processes such as centrifugation or filtration.

Inventors:

KIM DAE HEON (KR)
NA YUN JEONG (KR)
KIM JONGHAK (KR)
CHOI SEON (KR)

Application Number:

PCT/KR2023/014758

Publication Date:

April 04, 2024

Filing Date:

September 26, 2023

Export Citation:

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Assignee:

CCRIPO INC (KR)

International Classes:

C07K7/06; C07K1/34; C07K7/08; C12N15/62

Attorney, Agent or Firm:

YOU ME PATENT AND LAW FIRM (KR)

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