GASTRIC ACID SECRETION INHIBITOR, AND POTASSIUM CHANNEL INHIBITOR

WIPO Patent Application WO/2010/087150

A1

Disclosed are a pharmaceutical preparation, a quasi drug, a food, or a beverage each of which can act as a gastric acid secretion inhibitor or a potassium channel inhibitor and comprises a composition that can be used safely and can be produced at a low cost. Each of these products comprises at least one cool composition containing a compound capable of imparting a sensation of coolness, wherein the cool composition is contained in a sufficient amount for exhibiting the efficacy thereof in a living body to which each of the products is administered.

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SUZUKI YUICHI (JP)
ISHIDA KENYA (JP)
FUJIWHARA MITSUHIKO (JP)

PCT/JP2010/000424

August 05, 2010

January 26, 2010

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SHIZUOKA PREFECTURE PUBLIC UNI (JP)
TAKASAGO PERFUMERY CO LTD (JP)
SUZUKI YUICHI (JP)
ISHIDA KENYA (JP)
FUJIWHARA MITSUHIKO (JP)

A61K45/00; A23L1/30; A23L2/52; A61K31/045; A61K31/075; A61K31/16; A61P1/04; A61P1/10; A61P1/12; A61P3/10; A61P9/06; A61P9/10; A61P11/06; A61P37/08; A61P43/00

JP2008024690A	2008-02-07
JP2007269706A	2007-10-18
JP2006508016A	2006-03-09

WU, D.Z. ET AL.: "Palmatine, a protoberberine alkaloid, inhibits both Ca(2+)- and cAMP-activated Cl(-) secretion in isolated rat distal colon", BR J PHARMACOL, vol. 153, no. 6, 2008, pages 1203 - 13
ROEPKE, T.K. ET AL.: "The KCNE2 potassium channel ancillary subunit is essential for gastric acid secretion", J BIOL CHEM, vol. 281, no. 33, 2006, pages 23740 - 7

SHIMBO, Itsuki (JP)
Hitoshi Shimbo (JP)

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