Title:
GENE MANIPULATION FOR TREATMENT OF RETINAL DYSFUNCTION DISORDER
Document Type and Number:
WIPO Patent Application WO/2019/066549
Kind Code:
A2
Abstract:
The present invention relates to a gene manipulation composition for treatment or alleviation of retinal dysfunction disorder and a method using the same. More specifically, the present invention relates to a gene manipulation composition comprising a guide nucleic acid capable of targeting a retinogenesis gene and a method for treating or alleviating retinal dysfunction-caused diseases by which a retinogenesis gene is artificially manipulated and/or edited using the composition.
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Inventors:
LEE JUNG MIN (KR)
SONG DONG WOO (KR)
KIM UN GI (KR)
KIM JEONG HUN (KR)
JO DONG HYUN (KR)
SONG DONG WOO (KR)
KIM UN GI (KR)
KIM JEONG HUN (KR)
JO DONG HYUN (KR)
Application Number:
PCT/KR2018/011522
Publication Date:
April 04, 2019
Filing Date:
September 28, 2018
Export Citation:
Assignee:
TOOLGEN INC (KR)
SEOUL NAT UNIV R&DB FOUNDATION (KR)
SEOUL NAT UNIV HOSPITAL (KR)
SEOUL NAT UNIV R&DB FOUNDATION (KR)
SEOUL NAT UNIV HOSPITAL (KR)
International Classes:
C12N15/113; A61K48/00; A61P27/02; C12N9/22; C12N15/10; C12N15/86; C12N15/90
Other References:
LEE ET AL., NANO LETT., vol. 12, 2012, pages 6322 - 6327
JINEK ET AL., SCIENCE, vol. 343, no. 6176, 2014, pages 1247997
HIROSHI NISHIMASU ET AL., CELL, vol. 156, 2014, pages 935 - 949
ANDERS ET AL., NATURE, 2014
TAKASHI YAMANO ET AL., CELL, vol. 165, 2016, pages 949 - 962
JINEK ET AL., SCIENCE, vol. 343, no. 6176, 2014, pages 1247997
HIROSHI NISHIMASU ET AL., CELL, vol. 156, 2014, pages 935 - 949
ANDERS ET AL., NATURE, 2014
TAKASHI YAMANO ET AL., CELL, vol. 165, 2016, pages 949 - 962
Attorney, Agent or Firm:
IPS PATENT FIRM (KR)
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