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Title:
HEMOGLOBIN A1c MEASUREMENT METHOD AND MEASUREMENT KIT
Document Type and Number:
WIPO Patent Application WO/2015/060429
Kind Code:
A1
Abstract:
Provided is an amadoriase characterized in acting on the β-chains of hemoglobin A1c (HbA1c) to generate hydrogen peroxide. A HbA1c measurement method and measurement reagent kit using same are also provided. A HbA1c measurement method uses an amadoriase characterized in having a specific activity of 0.1 U/mg or more with respect to αF6P and in oxidizing the amino terminus of the β-chains of HbA1c to generate hydrogen peroxide, and a measurement reagent kit comprises said amadoriase. The present invention provides a measurement method and measurement kit that are able to quantify HbA1c rapidly, easily and with good precision.

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Inventors:
MASAKARI YOSUKE (JP)
ICHIYANAGI ATSUSHI (JP)
Application Number:
PCT/JP2014/078363
Publication Date:
April 30, 2015
Filing Date:
October 24, 2014
Export Citation:
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Assignee:
KIKKOMAN CORP (JP)
International Classes:
C12N15/09; C12N9/06; C12Q1/26; C12Q1/28
Domestic Patent References:
WO2004038034A12004-05-06
WO2004038033A12004-05-06
WO2011015325A12011-02-10
WO2008108385A12008-09-12
WO2013162035A12013-10-31
WO2004104203A12004-12-02
WO2005049857A12005-06-02
WO1997013872A11997-04-17
WO2010041715A12010-04-15
WO2010041419A12010-04-15
WO2011015325A12011-02-10
WO2004038034A12004-05-06
WO2008108385A12008-09-12
WO2007125779A12007-11-08
WO2012018094A12012-02-09
WO2011015326A22011-02-10
WO2008018094A12008-02-14
Foreign References:
JP2003235585A2003-08-26
JP2001095598A2001-04-10
JPH0533997B21993-05-20
JPH11127895A1999-05-18
JP2011229526A2011-11-17
JP2003235585A2003-08-26
JP2004275013A2004-10-07
JP2004275063A2004-10-07
JP2010035469A2010-02-18
JP2010057474A2010-03-18
JP2013222774A2013-10-28
Other References:
BIOCHEM. BIOPHYS. RES. COMMUN., vol. 311, 2003, pages 104 - 111
BIOTECHNOL. BIOENG., vol. 106, 2010, pages 358 - 366
J. BIOSCI. BIOENG., vol. 102, 2006, pages 241 - 243
APPL. MICROBIOL. BIOTECHNOL, vol. 74, 2007, pages 813 - 819
EUR. J. BIOCHEM., vol. 242, 1996, pages 499 - 505
MAR. BIOTECHNOL., vol. 6, 2004, pages 625 - 632
BIOSCI. BIOTECHNOL. BIOCHEM., vol. 66, 2002, pages 1256 - 1261
BIOSCI. BIOTECHNOL. BIOCHEM., vol. 66, 2002, pages 2323 - 2329
BIOTECHNOL. LETTERS, vol. 27, 2005, pages 27 - 32
JEPPSSON JO ET AL.: "Approved IFCC reference method for the measurement of HbAlc in human blood", CLIN. CHEM. LAB. MED., vol. 40, 2002, pages 78 - 89, XP002378412, DOI: doi:10.1515/CCLM.2002.016
SAMBROOK ET AL.: "Molecular Cloning", vol. 2, COLD SPRING HARBOR LABORATORY PRESS
"Current Protocols in Molecular Biology", 1987
"Current Protocols in Molecular Biology", 1989, WILEY INTERSCIENCE
GENDAI KAGAKU, June 1989 (1989-06-01), pages 24 - 30
NUCLEIC ACIDS RES., vol. 12, 1984, pages 9441
METHODS ENZYMOL., vol. 154, 1987, pages 350
GENE, vol. 37, 1985, pages 73
NUCLEIC ACIDS RES., vol. 13, 1985, pages 8749
NUCLEIC ACIDS RES., vol. 13, 1985, pages 8765
NUCLEIC ACIDS RES, vol. 14, 1986, pages 9679
PROC. NATL. ACID. SCI. U.S.A., vol. 82, 1985, pages 488
METHODS ENZYMOL., vol. 154, 1987, pages 367
CLIN. CHEM., vol. 43, 1997, pages 1994 - 1951
BIOTECHNOLOGY AND BIOENGINEERING, vol. 106, 2010, pages 358 - 366
PROTEIN SCI., vol. 4, 1995, pages 2411 - 2423
See also references of EP 3061819A4
Attorney, Agent or Firm:
HIRAKI Yusuke et al. (JP)
Yusuke Hiraki (JP)
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