(HALO-BENZO CARBONYL)HETEROCYCLO FUSED PHENYL P38 KINASE INHIBITING AGENTS

WIPO Patent Application WO2002058695

A9

Compounds described by the chemical formula (I) or a pharmaceutically acceptable salt thereof, are inhibitors of p38 useful in the treatment of inflammatory diseases such as arthritis.

DOHERTY JAMES B (US)
STELMACH JOHN E (US)
CHEN MENG-HSIN (US)
LIU LUPING (US)
HUNT JULIANNE A (US)
RUZEK ROWENA D (US)
GOULET JOUNG L (US)
WISNOSKI DAVID D (US)
NATARAJAN SWAMINATHAN RAVI (US)
RUPPRECHT KATHLEEN M (US)
BAO JIANMING (US)
MIAO SHOUWU (US)
HONG XINGFANG (US)

PCT/US2001/048676

September 12, 2003

December 14, 2001

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MERCK & CO INC (US)
DOHERTY JAMES B (US)
STELMACH JOHN E (US)
CHEN MENG-HSIN (US)
LIU LUPING (US)
HUNT JULIANNE A (US)
RUZEK ROWENA D (US)
GOULET JOUNG L (US)
WISNOSKI DAVID D (US)
NATARAJAN SWAMINATHAN RAVI (US)
RUPPRECHT KATHLEEN M (US)
BAO JIANMING (US)
MIAO SHOUWU (US)
HONG XINGFANG (US)

A61K31/4375; A61K31/4545; A61K31/4709; A61K31/496; A61K31/4995; A61K31/517; A61K31/519; A61K31/536; A61K31/5377; A61K31/55; A61P1/04; A61P7/00; A61P11/00; A61P11/06; A61P17/02; A61P17/06; A61P17/16; A61P19/02; A61P19/10; A61P25/04; A61P27/02; A61P29/00; A61P31/04; A61P31/16; A61P31/18; A61P31/20; A61P31/22; A61P33/06; A61P35/00; A61P37/00; A61P37/06; C07D215/22; C07D215/227; C07D221/06; C07D239/80; C07D265/18; C07D401/04; C07D401/12; C07D401/14; C07D403/04; C07D403/06; C07D403/12; C07D403/14; C07D405/04; C07D409/14; C07D417/12; C07D451/02; C07D471/04; C07D487/08; C07D519/00; C07D521/00; (IPC1-7): A61K31/395; A61K31/44; A61K31/47; A61K31/495; A61K31/50; A61K31/517; A61K31/519; A61K31/535; A61K31/55; A61P19/02; C07D239/72; C07D401/00; C07D403/00; C07D413/00; C07D471/00; C07D487/00

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