Title:
HETEROARYL DERIVATIVE CONTAINING N, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/048809
Kind Code:
A1
Abstract:
The present invention relates to a novel heteroaryl derivative compound containing N, a method for preparing same, a pharmaceutical composition comprising same as an active ingredient, and use thereof. The compound of the present invention exhibits high inhibitory activity against receptor tyrosine kinase so as to be effectively used for preventing or treating cancer caused by same.
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Inventors:
RYU HEESUN (KR)
LEE HWA (KR)
KANG SEIN (KR)
KO EUNHWA (KR)
CHOI HWANGEUN (KR)
KIM SUNGHWAN (KR)
LEE HWA (KR)
KANG SEIN (KR)
KO EUNHWA (KR)
CHOI HWANGEUN (KR)
KIM SUNGHWAN (KR)
Application Number:
PCT/KR2022/013004
Publication Date:
March 07, 2024
Filing Date:
August 31, 2022
Export Citation:
Assignee:
VORONOI INC (KR)
International Classes:
C07D495/04; A61K31/519; A61K31/53; A61P35/00; C07D487/04
Domestic Patent References:
| WO2010036910A1 | 2010-04-01 |
Foreign References:
| US20210323979A1 | 2021-10-21 | |||
| CN105153154A | 2015-12-16 | |||
| KR20160036053A | 2016-04-01 |
Other References:
MILIK SANDRA N.; ABDEL-AZIZ AMAL KAMAL; LASHEEN DEENA S.; SERYA RABAH A.T.; MINUCCI SAVERIO; ABOUZID KHALED A.M.: "Surmounting the resistance against EGFR inhibitors through the development of thieno[2,3-d]pyrimidine-based dual EGFR/HER2 inhibitors", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ELSEVIER, AMSTERDAM, NL, vol. 155, 6 June 2018 (2018-06-06), AMSTERDAM, NL , pages 316 - 336, XP085431298, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.06.011
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
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