Title:
HETEROCYCLE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONIST ACTIVITY
Document Type and Number:
WIPO Patent Application WO/2013/061977
Kind Code:
A1
Abstract:
The present invention pertains to the compound represented by formula (I) (in the formula: X1, X2, X3, X4, X5, R5, R6, R7, R8, n, p, q, ring A, and ring B have the same meaning as the definitions described in the description) or a pharmaceutically acceptable salt thereof.
Inventors:
HATA KAYOKO (JP)
MASUDA MANAMI (JP)
NAKAI HIROMI (JP)
TANIYAMA DAISUKE (JP)
TOBINAGA HIROYUKI (JP)
HATO YOSHIO (JP)
FUJIU MOTOHIRO (JP)
MASUDA MANAMI (JP)
NAKAI HIROMI (JP)
TANIYAMA DAISUKE (JP)
TOBINAGA HIROYUKI (JP)
HATO YOSHIO (JP)
FUJIU MOTOHIRO (JP)
Application Number:
PCT/JP2012/077393
Publication Date:
May 02, 2013
Filing Date:
October 24, 2012
Export Citation:
Assignee:
SHIONOGI & CO (JP)
International Classes:
C07D401/04; A61K31/416; A61K31/4178; A61K31/4196; A61K31/4439; A61K31/454; A61K31/46; A61P3/04; A61P9/00; A61P9/10; A61P11/00; A61P11/02; A61P11/06; A61P17/00; A61P25/00; A61P25/20; A61P25/28; A61P27/02; A61P27/12; A61P31/06; A61P33/10; A61P33/12; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07D401/14; C07D403/04; C07D403/14; C07D451/04
Domestic Patent References:
| WO2007029629A1 | 2007-03-15 | |||
| WO2003097598A1 | 2003-11-27 | |||
| WO2007010964A1 | 2007-01-25 | |||
| WO2007010965A1 | 2007-01-25 | |||
| WO2007037187A1 | 2007-04-05 | |||
| WO2007029629A1 | 2007-03-15 | |||
| WO2007010964A1 | 2007-01-25 | |||
| WO2007010965A1 | 2007-01-25 | |||
| WO2003097598A1 | 2003-11-27 | |||
| WO2005123731A2 | 2005-12-29 | |||
| WO2006034419A2 | 2006-03-30 | |||
| WO2005019208A1 | 2005-03-03 | |||
| WO2005123731A2 | 2005-12-29 | |||
| WO2006034419A2 | 2006-03-30 | |||
| WO2005019208A1 | 2005-03-03 | |||
| WO2004112793A1 | 2004-12-29 |
Foreign References:
| US4008070A | 1977-02-15 | |||
| US20080009497A1 | 2008-01-10 | |||
| EP0443498A1 | 1991-08-28 |
Other References:
See also references of EP 2752410A4
PHARMACOL. REV., vol. 46, 1994, pages 205 - 229
FARMACO, vol. 55, no. 1, 2000, pages 56 - 64
"Physical and Biomedical Sciences", vol. 1, 1987, article "Chapter 6"
"Design of Prodrugs", 1985, ELSEVIER
JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, no. 12, 1992, pages 2155 - 2162
ACTA CHEMICA SCANDINAVICA, vol. 52, 1998, pages 1214
MEDICINAL CHEMISTRY LETTERS, vol. 2, no. 2, 2011, pages 142 - 147
HETEROCYCLES, vol. 53, no. 1, 2000, pages 173 - 182
TETRAHEDRON, vol. 61, 2005, pages 3725 - 3731
ORGANIC AND BIOMOLECULAR CHEMISTRY, vol. 1, no. 19, 2003, pages 3277 - 3292
TETRAHEDRON:ASYMMETRY, vol. 13, pages 1103 - 1113
TETRAHEDRON, vol. 52, no. 47, 1996, pages 15017 - 15030
PHARMACOL. REV., vol. 46, 1994, pages 205 - 229
FARMACO, vol. 55, no. 1, 2000, pages 56 - 64
"Physical and Biomedical Sciences", vol. 1, 1987, article "Chapter 6"
"Design of Prodrugs", 1985, ELSEVIER
JOURNAL OF MEDICINAL CHEMISTRY, vol. 35, no. 12, 1992, pages 2155 - 2162
ACTA CHEMICA SCANDINAVICA, vol. 52, 1998, pages 1214
MEDICINAL CHEMISTRY LETTERS, vol. 2, no. 2, 2011, pages 142 - 147
HETEROCYCLES, vol. 53, no. 1, 2000, pages 173 - 182
TETRAHEDRON, vol. 61, 2005, pages 3725 - 3731
ORGANIC AND BIOMOLECULAR CHEMISTRY, vol. 1, no. 19, 2003, pages 3277 - 3292
TETRAHEDRON:ASYMMETRY, vol. 13, pages 1103 - 1113
TETRAHEDRON, vol. 52, no. 47, 1996, pages 15017 - 15030
Attorney, Agent or Firm:
TAKAYAMA, Hirotsugu et al. (JP)
Hiromitsu Takayama (JP)
Hiromitsu Takayama (JP)
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