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Title:
HETEROCYCLIC BETA-3 ADRENERGIC RECEPTOR AGONISTS
Document Type and Number:
WIPO Patent Application WO2002006229
Kind Code:
A3
Abstract:
This invetion provides compounds of Formula (1) having the structure (A), wherein U, V, W, X, and Y are as defined herinbefore, or a pharmaceutically acceptable salt thereof, which are useful in treating or inhibiting metabolic disorders related to insulin resistance or hyperglycemia (typically associated with obesity or glucose intolerance), atherosclerosis, gastrointestinal disorders, neurogenetic inflammation, glaucoma, ocular hypertension and frequent urination; and are particularly useful in the treatment or inhibition of type II diabetes.

Inventors:
ASHWELL MARK ANTHONY
SOLVIBILE WILLIAM RONALD
QUAGLIATO DOMINICK ANTHONY
MOLINARI ALBERT JOHN
Application Number:
PCT/US2001/022327
Publication Date:
July 25, 2002
Filing Date:
July 16, 2001
Export Citation:
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Assignee:
WYETH CORP (US)
International Classes:
C07D211/46; C07D211/54; C07D211/58; C07D211/60; C07D211/62; C07D211/96; C07D401/06; C07D401/12; C07D409/06; C07D409/14; C07D417/04; C07D417/12; (IPC1-7): C07D211/46; A61K31/445; A61K31/4468; A61K31/4525; A61K31/454; A61K31/4545; A61P1/00; A61P3/10; A61P9/10; A61P13/00; A61P27/06; A61P29/00; C07D211/54; C07D211/58; C07D211/96; C07D401/12; C07D405/12; C07D409/12
Domestic Patent References:
WO1995029159A11995-11-02
WO1999020607A11999-04-29
Foreign References:
EP0764640A11997-03-26
US5153210A1992-10-06
EP0070133A21983-01-19
DE2062055A11971-06-24
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