HETEROCYCLIC COMPOUND CAPABLE OF ENHANCING IMMUNE ACTIVITY, PREPARATION METHOD THEREFOR AND APPLICATION IN MEDICINE

Title:

HETEROCYCLIC COMPOUND CAPABLE OF ENHANCING IMMUNE ACTIVITY, PREPARATION METHOD THEREFOR AND APPLICATION IN MEDICINE

Document Type and Number:

WIPO Patent Application WO/2021/000770

Kind Code:

A1

Abstract:

A heterocyclic compound capable of enhancing immune activity, a preparation method therefor and an application in medicine. Specifically, provided is a compound represented by general formula (I), a preparation method therefor, and a pharmaceutical composition containing the derivative, as well as use thereof as a therapeutic agent, especially as a STING regulator and for treating STING-mediated diseases or disorders, such as inflammation, allergic and autoimmune diseases, infectious diseases, cancers, and precancerous syndromes.

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Inventors:

DENG YONGQI (CN)
SUN JIAN (CN)

Application Number:

PCT/CN2020/097941

Publication Date:

January 07, 2021

Filing Date:

June 24, 2020

Export Citation:

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Assignee:

CAMPHOR PHARMACEUTICALS LTD (CN)

International Classes:

A61K31/4184; A61P31/00; A61P35/00; A61P37/00; C07D403/14; C07D405/14

Domestic Patent References:

WO2017175156A1	2017-10-12
WO2020038387A1	2020-02-27

Foreign References:

CN109071514A

2018-12-21

Attorney, Agent or Firm:

GE CHENG & CO., LTD. (CN)

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