Title:
HIGH ACCURACY PROTEIN IDENTIFICATION
Document Type and Number:
WIPO Patent Application WO2002074927
Kind Code:
A3
Abstract:
The invention provides for the identification of target proteins in a sample based upon multiple sets of peptide fragment mass data obtained from the sample via gas phase ion spectroscopy. The sets of data are the product of analytical conditions that typically differ for each set such that cumulatively the data sets have higher information content than any individual set, thus enhancing the confidence level for accurate target protein identification. Probes, systems, and kits are additionally provided.
Inventors:
PHAM THANG T (US)
Application Number:
PCT/US2002/008450
Publication Date:
February 27, 2003
Filing Date:
March 18, 2002
Export Citation:
Assignee:
CIPHERGEN BIOSYSTEMS INC (US)
PHAM THANG T (US)
PHAM THANG T (US)
International Classes:
C07K1/12; C07K1/36; G01N33/68; (IPC1-7): B01D15/08; G01N30/02; G06F15/20
Other References:
MANN ET AL.: "Analysis of proteins and proteomes by mass spectrometry", ANNU. REV. BIOCHEM., vol. 70, 2001, pages 437 - 473, XP002955539
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