Title:
HIGH-AFFINITY T CELL RECEPTORS FOR RECOGNIZING MAGE AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/221959
Kind Code:
A1
Abstract:
Provided in the present application is a T cell receptor (TCR) having a property of binding to a GVYDGREHTV-HLA A0201 complex. Also provided in the present application are a multivalent TCR complex, a nucleic acid molecule encoding such TCRs, a vector containing the nucleic acids, a cell expressing such TCRs, and a pharmaceutical composition containing the foregoing substances. Further provided in the present application is a method for preparing such TCRs.
More Like This:
| WO/2019/165116 | COMPOSITIONS AND METHODS FOR CELLULAR IMMUNOTHERAPY |
| JP2023513706 | bispecific binding molecule |
| WO/1994/018317 | REGULATED TRANSCRIPTION OF TARGETED GENES AND OTHER BIOLOGICAL EVENTS |
Inventors:
HUANG JINHUA (CN)
ZHAN KAI (CN)
SHI DANFENG (CN)
WEN QIAOSHENG (CN)
CHEN YAOLONG (CN)
MEI YINGYI (CN)
ZHAN KAI (CN)
SHI DANFENG (CN)
WEN QIAOSHENG (CN)
CHEN YAOLONG (CN)
MEI YINGYI (CN)
Application Number:
PCT/CN2023/094407
Publication Date:
November 23, 2023
Filing Date:
May 16, 2023
Export Citation:
Assignee:
XLIFESC LTD (CN)
International Classes:
C07K14/725; A61K35/17; C07K14/47; C12N5/0783
Foreign References:
| CN109563148A | 2019-04-02 | |||
| CN109476724A | 2019-03-15 |
Attorney, Agent or Firm:
ADVANCE CHINA IP LAW OFFICE (CN)
Download PDF: