Title:
MICROFLUIDIC DEVICE, SYSTEM, KIT, METHOD OF ANALYZING NUCLEIC ACIDS, METHOD OF MANIPULATING NUCLEIC ACIDS, METHOD OF DETECTING A BIOMOLECULE, AND METHOD OF ANALYZING A BIOMOLECULE
Document Type and Number:
WIPO Patent Application WO/2023/221960
Kind Code:
A1
Abstract:
The present disclosure provides a microfluidic device, a system, a kit, a method of analyzing nucleic acids, a method of manipulating nucleic acids, a method of detecting a biomolecule, and a method of analyzing a biomolecule. The microfluidic device may include electrically conductive layers, to which an electric field can be applied to control movement of biomolecules associated with the single cell in the device. For example, polar molecules (e.g., RNA) of the cell can be captured (e.g. by barcode molecules) and analyzed with improved efficiency.
More Like This:
Inventors:
CHIU YUNYEN (CN)
QIAN MENGYA (CN)
TANG GUOXIN (CN)
ZHU WENQI (CN)
MA YANHONG (CN)
QIAN MENGYA (CN)
TANG GUOXIN (CN)
ZHU WENQI (CN)
MA YANHONG (CN)
Application Number:
PCT/CN2023/094410
Publication Date:
November 23, 2023
Filing Date:
May 16, 2023
Export Citation:
Assignee:
SINGLERON NANJING BIOTECHNOLOGIES LTD (CN)
International Classes:
C12M1/36; B01L3/00; C12Q1/6874
Domestic Patent References:
| WO2014207617A1 | 2014-12-31 |
Foreign References:
| CN112175824A | 2021-01-05 | |||
| CN101848757A | 2010-09-29 | |||
| CN103894248A | 2014-07-02 | |||
| US20030215937A1 | 2003-11-20 |
Attorney, Agent or Firm:
TEE & HOWE INTELLECTUAL PROPERTY ATTORNEYS (CN)
Download PDF: