Title:
HLA CLASS I AND II BINDING PEPTIDES AND THEIR USES
Document Type and Number:
WIPO Patent Application WO2003040165
Kind Code:
A3
Abstract:
The present invention provides the means and methods for selecting immunogenic peptides and the immunogenic peptide compositions capable of specifically binding glycoproteins encoded by HLA alleles and inducing T cell activation in T cells restricted by the allele. The peptides are useful to elicit an immune response against a desired antigen.
Inventors:
SETTE ALESSANDRO (US)
SIDNEY JOHN (US)
SOUTHWOOD SCOTT (US)
SIDNEY JOHN (US)
SOUTHWOOD SCOTT (US)
Application Number:
PCT/US2001/051650
Publication Date:
June 24, 2004
Filing Date:
October 18, 2001
Export Citation:
Assignee:
EPIMMUNE INC (US)
SETTE ALESSANDRO (US)
SIDNEY JOHN (US)
SOUTHWOOD SCOTT (US)
SETTE ALESSANDRO (US)
SIDNEY JOHN (US)
SOUTHWOOD SCOTT (US)
International Classes:
A61K39/385; (IPC1-7): A61K39/00; C07K2/00; C07H21/04
Other References:
V. H. ENGELHARD: "Structure of peptides associated with MHC class I molecules", CURRENT OPINION IN IMMUNOLOGY, vol. 6, February 1994 (1994-02-01), pages 13 - 23, XP002912059
RAMMENSEE H-G. ET AL.: "MHC ligands and peptide motifs: first listing", IMMUNOGENETICS, vol. 41, 1995, pages 178 - 228, XP002919644
RAMMENSEE H-G. ET AL.: "MHC ligands and peptide motifs: first listing", IMMUNOGENETICS, vol. 41, 1995, pages 178 - 228, XP002919644
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