Title:
HYALURONATE NANOFABRIC SHEET AND MANUFACTURING METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO/2023/191385
Kind Code:
A1
Abstract:
The present invention relates to a hyaluronate nanofabric sheet and a manufacturing method therefor and, more particularly, to a hyaluronate nanofabric sheet having excellent percutaneous absorption and physical properties and a manufacturing method therefor. A method for manufacturing a hyaluronate nanofabric sheet according to the present invention comprises the steps of: (a) mixing a hyaluronate having a weight average molecular weight of 5×103 - 5×104 Da and a hyaluronate having a weight average molecular weight of 1×105 - 1×106Da and dissolving same in water to prepare an aqueous hyaluronate solution; and (b) electrospinning the aqueous hyaluronate solution. The hyaluronate nanofabric sheet of the present invention has an excellent transdermal absorption rate due to the ultra-low molecular weight hyaluronic acid as a main component thereof and exhibits excellent physical properties due to a certain amount of medium-molecular weight hyaluronic acid mixed therewith, and as such, can be applied for various purposes, such as mask patches for topical uses, ophthalmic or mucosal drug delivery systems, etc.
Inventors:
KWEON DONG KEON (KR)
LEE MYOUNG HAN (KR)
KIM JONG SOO (KR)
HONG JOO YEON (KR)
LEE MYOUNG HAN (KR)
KIM JONG SOO (KR)
HONG JOO YEON (KR)
Application Number:
PCT/KR2023/003879
Publication Date:
October 05, 2023
Filing Date:
March 23, 2023
Export Citation:
Assignee:
JINWOO BIO CO LTD (KR)
International Classes:
D04H1/4266; A45D44/00; A61K8/02; A61K8/73; A61K9/70; A61K47/36; A61Q19/00; D04H1/485; D04H1/728
Foreign References:
| KR102338355B1 | 2021-12-22 | |||
| KR20110116616A | 2011-10-26 | |||
| KR20200117191A | 2020-10-14 | |||
| KR20110110482A | 2011-10-07 | |||
| KR101709608B1 | 2017-03-09 | |||
| KR102475486B1 | 2022-12-08 |
Attorney, Agent or Firm:
HAEDAM IP GROUP (KR)
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