HYDROXAMIC ACID DERIVATIVE AND MMP INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT

Title:

HYDROXAMIC ACID DERIVATIVE AND MMP INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT

Document Type and Number:

WIPO Patent Application WO/2003/055851

Kind Code:

A1

Abstract:

A hydroxamic acid derivative represented by the following general formula (1), which has selective MMP inhibitory activity: (1) wherein R¹ and R² each represents hydrogen, lower alkyl, lower haloalkyl, etc.; X represents methylene or NR³ (R³ represents hydrogen, lower alkyl, etc.); and R⁴ represents C_1-4 alkyl.

Inventors:

HORIUCHI YOSHIHIRO (JP)

Application Number:

PCT/JP2002/013580

Publication Date:

July 10, 2003

Filing Date:

December 26, 2002

Export Citation:

Click for automatic bibliography generation Help

Assignee:

SUMITOMO PHARMA (JP)
HORIUCHI YOSHIHIRO (JP)

International Classes:

A61P19/02; A61P29/00; A61P43/00; C07C317/22; C07D213/42; C07D241/04; C07D265/30; C07D279/16; C07D295/195; C07D309/08; C07D309/14; C07D405/06; (IPC1-7): C07C317/22; C07D213/42; C07D279/16; C07D295/18; C07D309/14; C07D309/08; A61K31/10; A61K31/18; A61K31/351; A61K31/4406; A61K31/4409; A61K31/5375; A61K31/5415; A61P19/02; A61P29/00; A61P43/00

Domestic Patent References:

WO2000071514A1	2000-11-30
WO2000063197A1	2000-10-26
WO1998050348A1	1998-11-12
WO1999007675A1	1999-02-18

Foreign References:

EP0780386A1

1997-06-25

Other References:

SANTOS ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. 14, 2006, pages 7539 - 7550
REITER ET AL., BIOORGANIC & MEDICINAL CHEMISTRY, vol. 14, 2004, pages 3389 - 3395
See also references of EP 1466899A4

Attorney, Agent or Firm:

Aoyama, Tamotsu (IMP Building 3-7, Shiromi 1-chome, Chuo-k, Osaka-shi Osaka, JP)

Download PDF:

View/Download PDF PDF Help

Previous Patent: METHOD FOR PRODUCING QUATERNARY SALT PHENOLATE SOLUTIONS AND FOR REGENERATING AND RECYCLING QUATERNA...

Next Patent: MULTIFUNCTIONAL REAGENT FOR THE SYNTHESIS OF THIOL MODIFIED OLIGOMERS