Title:
HYPERTRIGLYCERIDEMIA REMEDIES AND ANTIOBESTICS
Document Type and Number:
WIPO Patent Application WO/2001/027094
Kind Code:
A1
Abstract:
Triglyceride inhibitors containing compounds of general formula (I) and being useful as hypertriglyceridemia remedies or antiobestics, [wherein R?1¿ is C¿1-6? alkyl or a group represented by general formula (II) or (III) (wherein R?11¿ is optionally substituted C¿1-6? alkyl or the like; R?12¿ is halogeno, hydroxyl, C¿1-6? alkoxy, optionally substituted amino, or the like; and Y?1¿ is oxygen or the like); R?2¿ is C¿1-6? alkyl, C¿3-7? cycloalkyl, or the like; and R?3¿ is optionally substituted phenyl, optionally substituted thienyl, optionally substituted furyl, or the like); and novel thiazole compounds useful as hypertriglyceridemia remedies, antiobestics or the like.
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Inventors:
YATA SHINJI (JP)
HASHIMOTO HIROMASA (JP)
ODANI NAOYA (JP)
HASHIMOTO HIROMASA (JP)
ODANI NAOYA (JP)
Application Number:
PCT/JP2000/007016
Publication Date:
April 19, 2001
Filing Date:
October 06, 2000
Export Citation:
Assignee:
JAPAN TOBACCO INC (JP)
YATA SHINJI (JP)
HASHIMOTO HIROMASA (JP)
ODANI NAOYA (JP)
YATA SHINJI (JP)
HASHIMOTO HIROMASA (JP)
ODANI NAOYA (JP)
International Classes:
A61K31/426; A61K31/427; A61K31/4439; A61P3/04; A61P3/06; C07D277/24; C07D277/28; C07D277/30; C07D277/56; C07D417/04; (IPC1-7): C07D277/24; A61K31/426; A61K31/427; A61K31/4439; A61P3/04; A61P3/06; C07D277/28; C07D277/30; C07D277/56; C07D417/04
Domestic Patent References:
| WO1996003392A1 | 1996-02-08 | |||
| WO1999021555A2 | 1999-05-06 |
Foreign References:
| US4632930A | 1986-12-30 | |||
| EP0611003A1 | 1994-08-17 | |||
| EP0745600A1 | 1996-12-04 |
Other References:
GORDON T.D. ET AL.: "Synthetic approaches to the 'Azole' peptide mimetics", TETRAHEDRON LETT., vol. 34, no. 12, 1993, pages 1901 - 1904, XP002935432
Attorney, Agent or Firm:
Takashima, Hajime (Fushimimachi 4-chome Chuo-ku Osaka-shi Osaka, JP)
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