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Title:
INHIBITORS OF FACTOR Xa
Document Type and Number:
WIPO Patent Application WO2000071507
Kind Code:
A3
Abstract:
Novel compounds, their salts and compositions related thereto having activity against mammalian factor Xa are disclosed. The compounds are useful in vitro or in vivo for preventing or treating coagulation disorders.

Inventors:
ZHU BING-YAN
SU TING
ZHAOZHONG JON JIA
SCARBOROUGH ROBERT M
SONG YONGHONG
Application Number:
PCT/US2000/014196
Publication Date:
November 15, 2001
Filing Date:
May 24, 2000
Export Citation:
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Assignee:
COR THERAPEUTICS INC (US)
International Classes:
A61K31/167; A61K31/18; A61K31/275; A61K31/277; A61P7/02; A61K31/40; A61K31/472; A61K31/4725; A61P9/00; A61P9/04; A61P9/10; C07C311/16; C07C311/18; C07C311/40; C07C311/44; C07C311/46; C07D207/16; C07D217/22; C07D401/06; (IPC1-7): C07C311/46; C07C311/18; A61K31/18; A61K31/275
Domestic Patent References:
WO1999011658A11999-03-11
WO1999012903A11999-03-18
WO1999011657A11999-03-11
Foreign References:
US5886191A1999-03-23
EP0976722A12000-02-02
EP1020434A12000-07-19
US4070176A1978-01-24
Other References:
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002166636
R. KARAMAN ET AL, TETRAHEDRON LETT., vol. 31, no. 7, 1990, pages 941 - 944, XP002166634
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002166637
P.O. BURKE ET AL, J. CHEM. SOC. PERKIN TRANS. II, no. 11, 1984, pages 1851 - 1854, XP002166629
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