Title:
IMIDAZO-PYRIMIDONE COMPOUNDS, AND PREPARATION METHOD AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/184437
Kind Code:
A1
Abstract:
Disclosed are imidazo-pyrimidone compounds as shown in formula (I), and a preparation method and an application of said compounds. n, R and Ar are described in the description. The compounds and pharmaceutically acceptable salts thereof trigger the production of the tumour necrosis factor-related apoptosis-inducing ligand in the human body, and also prevent the misuse of existing recombinant protein and antibody-based treatment means, thereby providing a new choice for related tumour treatment.
Inventors:
XU RUO (CN)
LIU YUNYONG (CN)
LIU YUNYONG (CN)
Application Number:
PCT/CN2016/086145
Publication Date:
November 24, 2016
Filing Date:
June 17, 2016
Export Citation:
Assignee:
NANJING GATOR MEDITECH COMPANY LTD (CN)
International Classes:
C07D471/14; A61K31/519; A61K31/5377; A61P35/00; C07D487/14
Domestic Patent References:
| WO2015153468A1 | 2015-10-08 | |||
| WO2014160130A1 | 2014-10-02 |
Foreign References:
| CN104860948A | 2015-08-26 | |||
| US20140335048A1 | 2014-11-13 |
Attorney, Agent or Firm:
SHIJIAZHUANG GUOYU PATENT TRADEMARK AGENCY (CN)
石家庄国域专利商标事务所有限公司 (CN)
石家庄国域专利商标事务所有限公司 (CN)
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