Title:
NEW CRYSTAL FORM OF LENVATINIB METHANESULFONATE SALT AND PREPARATION METHOD THEREOF
Document Type and Number:
WIPO Patent Application WO/2016/184436
Kind Code:
A1
Abstract:
The present invention relates to a new crystal form of a Lenvatinib methanesulfonate salt and a preparation method thereof. The new crystal form of the Lenvatinib methanesulfonate salt provided in the present invention can be used for treating invasive and differentiated thyroid cancer. The new crystal form of the Lenvatinib methanesulfonate salt provided in the present invention has a good solubility and stability, significant effects in the purification process, a simple preparation method and low cost, and has an important value for the optimization and development of this drug in future.
Inventors:
CHEN MINHUA (CN)
ZHANG YANFENG (CN)
DIAO XIAOJUAN (CN)
ZHANG XIAOYU (CN)
ZHANG YANFENG (CN)
DIAO XIAOJUAN (CN)
ZHANG XIAOYU (CN)
Application Number:
PCT/CN2016/085360
Publication Date:
November 24, 2016
Filing Date:
June 08, 2016
Export Citation:
Assignee:
CRYSTAL PHARMATECH CO LTD (CN)
International Classes:
C07D215/48; A61K31/47; A61P35/00
Foreign References:
| CN100569753C | 2009-12-16 | |||
| CN101001629A | 2007-07-18 |
Other References:
See also references of EP 3287444A4
Attorney, Agent or Firm:
SUZHOU CREATOR PATENT & TREADMARK AGENCY LTD. (CN)
苏州创元专利商标事务所有限公司 (CN)
苏州创元专利商标事务所有限公司 (CN)
Download PDF: