Title:
IMMUNOCHROMATOGRAPHY KIT, AND METHOD FOR DETECTING MYCOBACTERIUM TUBERCULOSIS
Document Type and Number:
WIPO Patent Application WO/2020/045625
Kind Code:
A1
Abstract:
The objective of the present invention is to provide an immunochromatography kit and method with which it is possible to detect mycobacterium tuberculosis specifically and with a high degree of sensitivity. The present invention provides an immunochromatography kit for detecting mycobacterium tuberculosis, including a labeling substance modified using a first antibody for lipoarabinomannan, a porous carrier having a reaction site holding a second antibody for lipoarabinomannan, a compound containing silver, and a reducing agent capable of reducing silver ions, wherein at least one of the first antibody and the second antibody is a monoclonal antibody.
Inventors:
OHARA TOMOYA (JP)
OYABU NATSUKI (JP)
WADA ATSUHIKO (JP)
KATADA JUNICHI (JP)
UJIHARA DAI (JP)
OYABU NATSUKI (JP)
WADA ATSUHIKO (JP)
KATADA JUNICHI (JP)
UJIHARA DAI (JP)
Application Number:
PCT/JP2019/034112
Publication Date:
March 05, 2020
Filing Date:
August 30, 2019
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
G01N33/569; G01N33/543; C07K16/12
Domestic Patent References:
| WO2013129634A1 | 2013-09-06 | |||
| WO2013129634A1 | 2013-09-06 | |||
| WO2017139153A1 | 2017-08-17 | |||
| WO2012102679A1 | 2012-08-02 |
Foreign References:
| JP2013213803A | 2013-10-17 | |||
| JP2016099283A | 2016-05-30 | |||
| JP2008507544A | 2008-03-13 | |||
| US6020117A | 2000-02-01 |
Other References:
LAWN, SD: "Point-of-care detection of lipoarabinomannan (LAM) in urine for diagnosis of HIV-associated tuberculosis: a state of the art review", BMC INFECTIOUS DISEASES, vol. 12, 26 April 2012 (2012-04-26), pages 103, XP021132590
CHOUDHARY, A. ET AL.: "Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen", THE JOURNAL OF IMMUNOLOGY, vol. 200, no. 9, 1 May 2018 (2018-05-01), pages 3053 - 3066, XP055621331, DOI: 10.4049/jimmunol.1701673
BMC INFECTIOUS DISEASES, vol. 12, 2012, pages 103
J IMMUNOL., vol. 200, no. 9, 1 May 2018 (2018-05-01), pages 3053 - 3066
ACCORDING TO J IMMUNOL., vol. 200, no. 9, 1 May 2018 (2018-05-01), pages 3053 - 3066
NATURE PHYSICAL SCIENCE, vol. 241, 1973, pages 20
THE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY, vol. 30, no. 7, 1982, pages 691 - 696
SHINICHI KIKUCHI ET AL.: "Fundamentals of Photograph Engineering (Revised) -Silver Halide Photography", SHASHINKOGYO PUBLISHING COMPANY
CHOUDHARY, A. ET AL.: "Characterization of the Antigenic Heterogeneity of Lipoarabinomannan, the Major Surface Glycolipid of Mycobacterium tuberculosis, and Complexity of Antibody Specificities toward This Antigen", THE JOURNAL OF IMMUNOLOGY, vol. 200, no. 9, 1 May 2018 (2018-05-01), pages 3053 - 3066, XP055621331, DOI: 10.4049/jimmunol.1701673
BMC INFECTIOUS DISEASES, vol. 12, 2012, pages 103
J IMMUNOL., vol. 200, no. 9, 1 May 2018 (2018-05-01), pages 3053 - 3066
ACCORDING TO J IMMUNOL., vol. 200, no. 9, 1 May 2018 (2018-05-01), pages 3053 - 3066
NATURE PHYSICAL SCIENCE, vol. 241, 1973, pages 20
THE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY, vol. 30, no. 7, 1982, pages 691 - 696
SHINICHI KIKUCHI ET AL.: "Fundamentals of Photograph Engineering (Revised) -Silver Halide Photography", SHASHINKOGYO PUBLISHING COMPANY
Attorney, Agent or Firm:
SIKs & Co. (JP)
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