IMPROVED PROCESSES FOR THE PREPARATION OF HIGHLY PURE RIVAROXABAN CRYSTAL MODIFICATION I

Title:

IMPROVED PROCESSES FOR THE PREPARATION OF HIGHLY PURE RIVAROXABAN CRYSTAL MODIFICATION I

Document Type and Number:

WIPO Patent Application WO/2015/111076

Kind Code:

A3

Abstract:

Provided herein are improved, commercially viable and consistently reproducible processes for the preparation of highly pure crystal Modification I of Rivaroxaban, which is free from other polymorphs and undesired solvated forms. Provided also herein is a highly pure and stable crystal Modification I of Rivaroxaban essentially free of other solid state forms.

Inventors:

MOHAN RAO DODDA (IN)
VENUGOPAL BINGI (IN)

Application Number:

PCT/IN2015/000031

Publication Date:

November 12, 2015

Filing Date:

January 19, 2015

Export Citation:

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Assignee:

SYMED LABS LTD (IN)
MOHAN RAO DODDA (IN)
VENUGOPAL BINGI (IN)

International Classes:

A61K31/5377

Domestic Patent References:

WO2013164833A1	2013-11-07
WO2011012321A1	2011-02-03
WO2013121436A2	2013-08-22

Foreign References:

US7585860B2	2009-09-08
US8188270B2	2012-05-29
US20110152266A1	2011-06-23

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