IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION

Title:

IN VIVO GELLING PHARMACEUTICAL PRE-FORMULATION

Document Type and Number:

WIPO Patent Application WO/2011/140519

Kind Code:

A3

Abstract:

Provided herein are in vivo gelling pharmaceutical pre-formulations forming biocompatible hydrogel polymers that are polymerized in vivo and kits comprising at least one nucleophilic compound or monomer unit, at least one electrophilic compound or monomer unit, and optionally at least one therapeutic agent. The biocompatible hydrogel polymer is bioabsorbable and releases the therapeutic agent at a target site, avoiding systemic exposure.

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Inventors:

ASKARI SYED H (US)
HORNG GEORGE (US)

Application Number:

PCT/US2011/035643

Publication Date:

March 29, 2012

Filing Date:

May 06, 2011

Export Citation:

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Assignee:

MEDICUS BIOSCIENCES LLC (US)
ASKARI SYED H (US)
HORNG GEORGE (US)

International Classes:

A61K47/48; A61K9/06; A61K47/30; A61K49/10; A61P31/12; A61P35/00

Foreign References:

US20090196928A1	2009-08-06
US20080279944A1	2008-11-13
US20020106409A1	2002-08-08

Attorney, Agent or Firm:

HOSTETLER, Michael, J. et al. (650 Page Mill RoadPalo Alto, CA, US)

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