INDUCTION OF CELLULAR SENESCENCE BY CDK4 DISRUPTION FOR TUMOR SUPRESSION AND REGRESSION

Title:

INDUCTION OF CELLULAR SENESCENCE BY CDK4 DISRUPTION FOR TUMOR SUPRESSION AND REGRESSION

Document Type and Number:

WIPO Patent Application WO2004044226

Kind Code:

A3

Abstract:

The invention provides methods of inhibiting growth of tumor cells comprising contacting the cells with a Cdk4 inhibitor. The invention also provides methods of treating patients having, suspected of having, or at a high risk for developing, a cancer, comprising treatment with a Cdk4 inhibitor. The invention also relates to pharmaceutical compositions for treating such patients, wherein the pharmaceutical compositions comprise a Cdk4 inhibitor.

Inventors:

KIYOKAWA HIROAKI (US)
ZOU XIANGHONG (US)

Application Number:

PCT/US2003/036037

Publication Date:

February 17, 2005

Filing Date:

November 12, 2003

Export Citation:

Click for automatic bibliography generation Help

Assignee:

UNIV ILLINOIS (US)
KIYOKAWA HIROAKI (US)
ZOU XIANGHONG (US)

International Classes:

A01N43/04; A61K38/00; C12N15/113; G01N33/48; G01N33/50; C12Q; (IPC1-7): A61K38/00; A01N43/04; G01N33/48

Foreign References:

US6221873B1	2001-04-24
US5596079A	1997-01-21
US20010047019A1	2001-11-29
US5962316A	1999-10-05

Download PDF:

View/Download PDF PDF Help

Previous Patent: METHODS FOR IDENTIFYING DNA COPY NUMBER CHANGES

Next Patent: ETHYLENEDICYSTEINE (EC)-DRUG CONJUGATES, COMPOSITIONS AND METHODS FOR TISSUE SPECIFIC DISEASE IMAGIN...