INDUCTION OF IMMUNE RESPONSES TO ISOASPARTYL-MODIFIED ANTIGENS

Title:

INDUCTION OF IMMUNE RESPONSES TO ISOASPARTYL-MODIFIED ANTIGENS

Document Type and Number:

WIPO Patent Application WO2002060390

Kind Code:

A3

Abstract:

The present invention is directed to a method of enhancing the immune response of a patient relative to the normal immune response, by administering isoaspartyl-modified proteins, peptides, or cells, to a patient. The present invention is also directed to vaccines containing the isoaspartyl-modified proteins, peptides, or cells, as well as antibodies reactive with the isoaspartyl-modified proteins, peptides, or cells.

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Inventors:

MAMULA MARK J (US)

Application Number:

PCT/US2002/000336

Publication Date:

October 03, 2002

Filing Date:

January 04, 2002

Export Citation:

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Assignee:

UNIV YALE (US)
MAMULA MARK J (US)

International Classes:

A61K39/00; (IPC1-7): A61K39/00; A61K45/00; A61K47/00

Domestic Patent References:

WO1997033612A1

1997-09-18

Foreign References:

US5582831A	1996-12-10
US5965381A	1999-10-12
US5872104A	1999-02-16
US5733540A	1998-03-31

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