METHOD TO TREAT CHRONIC HEART FAILURE AND/OR ELEVATED CHOLESTEROL LEVELS USING 3,5-DIIODOTHYROPROPIONIC ACID AND METHOD TO PREPARE SAME

Title:

METHOD TO TREAT CHRONIC HEART FAILURE AND/OR ELEVATED CHOLESTEROL LEVELS USING 3,5-DIIODOTHYROPROPIONIC ACID AND METHOD TO PREPARE SAME

Document Type and Number:

WIPO Patent Application WO2002060389

Kind Code:

A3

Abstract:

Applicants's invention includes a method to treat a patient having congestive heart failure by administering a therapeutically effective amount of 3,5-diiodothyropropionic acid. Applicants' invention further includes a method to lower cholesterol blood levels of a patient by administering a therapeutically effective amount of 3,5-diiodothyropropionic acid. Aplicants' invention further includes a synthetic method to prepare 3,5-diiodothyropropionic acid.

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Inventors:

GOLDMAN STEVEN (US)
PENNOCK GREGORY D (US)
MORKIN EUGENE
BAHL JOSEPH J

Application Number:

PCT/US2002/003162

Publication Date:

April 15, 2004

Filing Date:

January 31, 2002

Export Citation:

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Assignee:

UNIV ARIZONA (US)
GOLDMAN STEVEN (US)
PENNOCK GREGORY D (US)

International Classes:

A61K9/48; A61K9/08; A61K9/72; A61K31/192; A61K31/195; A61P9/04; C07C43/225; C07C51/09; C07C51/363; C07C53/18; C07C57/30; C07C67/08; C07C69/712; A61K9/70; (IPC1-7): A01N37/12; A01N37/44

Foreign References:

US5561151A	1996-10-01
US5981592A	1999-11-09
US5331000A	1994-07-19

Other References: