Title:
INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF
Document Type and Number:
WIPO Patent Application WO/2024/002157
Kind Code:
A1
Abstract:
Provided are FGFR2 and FGFR3 inhibitors of Formula (I) and pharmaceutical compositions comprising said inhibitors. The compounds and compositions are useful for the treatment of a disease or disorder associated with FGFR2 and/or FGFR3.
Inventors:
DING XIAO (CN)
LIU YINGTAO (CN)
WANG YAZHOU (CN)
WU JIANPING (CN)
LIU JINXIN (CN)
LIU YINGTAO (CN)
WANG YAZHOU (CN)
WU JIANPING (CN)
LIU JINXIN (CN)
Application Number:
PCT/CN2023/103171
Publication Date:
January 04, 2024
Filing Date:
June 28, 2023
Export Citation:
Assignee:
INSILICO MEDICINE IP LTD (CN)
International Classes:
C07D487/04; A61K31/53; A61P35/00; C07D471/04
Domestic Patent References:
| WO2023104035A1 | 2023-06-15 | |||
| WO2011161537A2 | 2011-12-29 | |||
| WO2020231990A1 | 2020-11-19 | |||
| WO2009136966A1 | 2009-11-12 | |||
| WO2004099213A2 | 2004-11-18 | |||
| WO2017192929A1 | 2017-11-09 | |||
| WO2010071885A1 | 2010-06-24 |
Other References:
MEHTA LINA K., PARRICK JOHN: "The synthesis of three indolizine derivatives of interest as non‐isomerizable analogues of tamoxifen", JOURNAL OF HETEROCYCLIC CHEMISTRY, WILEY-BLACKWELL PUBLISHING, INC., US, vol. 32, no. 2, 1 March 1995 (1995-03-01), US , pages 391 - 394, XP093124693, ISSN: 0022-152X, DOI: 10.1002/jhet.5570320203
Attorney, Agent or Firm:
AFD CHINA INTELLECTUAL PROPERTY LAW OFFICE (CN)
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