Title:
INSULIN RESISTANCE-IMPROVING AGENT
Document Type and Number:
WIPO Patent Application WO/2007/105730
Kind Code:
A1
Abstract:
Disclosed is a safe and highly effective insulin resistance-improving agent or hyperinsulinism-ameliorating agent. The insulin resistance-improving agent or hyperinsulinism-ameliorating agent comprises hydroxyproline, an N-acylated derivative of hydroxyproline or a salt of hydroxyproline or the N-acylated derivative and a biguanide as active ingredients.
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Inventors:
KAMIYA TOSHIKAZU
OGINO FUMIKO
OGINO FUMIKO
Application Number:
PCT/JP2007/054973
Publication Date:
September 20, 2007
Filing Date:
March 13, 2007
Export Citation:
Assignee:
KYOWA HAKKO KOGYO KK (JP)
KAMIYA TOSHIKAZU
OGINO FUMIKO
KAMIYA TOSHIKAZU
OGINO FUMIKO
International Classes:
A61K31/401; A61K31/155; A61P3/10
Domestic Patent References:
WO2004083179A1 | 2004-09-30 | |||
WO2005110394A1 | 2005-11-24 | |||
WO2002041879A2 | 2002-05-30 | |||
WO2006131836A2 | 2006-12-14 | |||
WO2006120574A2 | 2006-11-16 | |||
WO2006044391A1 | 2006-04-27 |
Foreign References:
JPH09104624A | 1997-04-22 | |||
JPS63218621A | 1988-09-12 | |||
EP0749751A2 | 1996-12-27 |
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