Title:
INTRACELLULAR SIGNALING MOLECULES
Document Type and Number:
WIPO Patent Application WO2002077235
Kind Code:
A3
Abstract:
The invention provides human intracellular signaling molecules (INTSIG) and polynucleotides which identify and encode INTSIG. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of INTSIG.
Inventors:
BURFORD NEIL (US)
DING LI (US)
YUE HENRY (US)
THORNTON MICHAEL (US)
CHAWLA NARINDER K (US)
GANDHI AMEENA R (US)
ARVIZU CHANDRA (US)
BAUGHN MARIAH R (US)
SWARNAKAR ANITA (US)
DUGGAN BRENDAN M (US)
LU DYUNG AINA M (US)
THANGAVELU KAVITHA (US)
WARREN BRIDGET A (US)
TANG Y TOM (US)
KHAN FARRAH A (US)
YAO MONIQUE G (US)
EMERLING BROOKE M (US)
DING LI (US)
YUE HENRY (US)
THORNTON MICHAEL (US)
CHAWLA NARINDER K (US)
GANDHI AMEENA R (US)
ARVIZU CHANDRA (US)
BAUGHN MARIAH R (US)
SWARNAKAR ANITA (US)
DUGGAN BRENDAN M (US)
LU DYUNG AINA M (US)
THANGAVELU KAVITHA (US)
WARREN BRIDGET A (US)
TANG Y TOM (US)
KHAN FARRAH A (US)
YAO MONIQUE G (US)
EMERLING BROOKE M (US)
Application Number:
PCT/US2001/050315
Publication Date:
November 20, 2003
Filing Date:
December 19, 2001
Export Citation:
Assignee:
INCYTE GENOMICS INC (US)
BURFORD NEIL (US)
DING LI (US)
YUE HENRY (US)
THORNTON MICHAEL (US)
CHAWLA NARINDER K (US)
GANDHI AMEENA R (US)
ARVIZU CHANDRA (US)
BAUGHN MARIAH R (US)
SWARNAKAR ANITA (US)
DUGGAN BRENDAN M (US)
LU DYUNG AINA M (US)
THANGAVELU KAVITHA (US)
WARREN BRIDGET A (US)
TANG Y TOM (US)
KHAN FARRAH A (US)
YAO MONIQUE G (US)
EMERLING BROOKE M (US)
BURFORD NEIL (US)
DING LI (US)
YUE HENRY (US)
THORNTON MICHAEL (US)
CHAWLA NARINDER K (US)
GANDHI AMEENA R (US)
ARVIZU CHANDRA (US)
BAUGHN MARIAH R (US)
SWARNAKAR ANITA (US)
DUGGAN BRENDAN M (US)
LU DYUNG AINA M (US)
THANGAVELU KAVITHA (US)
WARREN BRIDGET A (US)
TANG Y TOM (US)
KHAN FARRAH A (US)
YAO MONIQUE G (US)
EMERLING BROOKE M (US)
International Classes:
C07K14/47; C12N15/12; C12Q1/68; A61K38/00; (IPC1-7): C12N15/12; A61K45/00; C07K14/47; C07K16/18; C12Q1/68; G01N33/53
Foreign References:
| EP1074617A2 | 2001-02-07 |
Other References:
DATABASE EMBL [online] 23 March 2001 (2001-03-23), "Human secreted protein gene 17 SEQ ID NO:27", XP002233902, retrieved from EBI Database accession no. AAF32715
DATABASE EMBL [online] 23 March 2001 (2001-03-23), "Human secreted protein sequence encoded by gene 17 SEQ ID NO:76", XP002233903, retrieved from EBI Database accession no. AAB64438
DATABASE EMBL [online] 30 November 2001 (2001-11-30), "Human ARF-like protein encoding cDNA (clone C-HEMBA1001174)", XP002233904, retrieved from EBI Database accession no. AAH47115
DATABASE EMBL [online] 30 November 2001 (2001-11-30), "Human ARF-like protein (clone C-HEMBA1001174)", XP002233905, retrieved from EBI Database accession no. AAB85882
DATABASE EMBL [online] 6 January 2000 (2000-01-06), "xv32f07.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:2814853 3' similar to SW:ARL5_RAT P51646 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5; mRNA sequence", XP002233906, retrieved from EBI Database accession no. AW274697
DATABASE EMBL [online] 30 August 2002 (2002-08-30), "Human novel polynucleotide #89", XP002233907, retrieved from EBI Database accession no. ABK94978
DATABASE EMBL [online] 30 August 2002 (2002-08-30), "Human novel polypeptide #89", XP002233908, retrieved from EBI Database accession no. ABG66754
TANAKA N ET AL: "A NOVEL HUMAN TYROSINE KINASE GENE INDUCIBLE IN T CELLS BY INTERLEUKIN 2", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 324, no. 1, June 1993 (1993-06-01), pages 1 - 5, XP001108908, ISSN: 0014-5793
DATABASE EMBL [online] 23 March 2001 (2001-03-23), "Human secreted protein sequence encoded by gene 17 SEQ ID NO:76", XP002233903, retrieved from EBI Database accession no. AAB64438
DATABASE EMBL [online] 30 November 2001 (2001-11-30), "Human ARF-like protein encoding cDNA (clone C-HEMBA1001174)", XP002233904, retrieved from EBI Database accession no. AAH47115
DATABASE EMBL [online] 30 November 2001 (2001-11-30), "Human ARF-like protein (clone C-HEMBA1001174)", XP002233905, retrieved from EBI Database accession no. AAB85882
DATABASE EMBL [online] 6 January 2000 (2000-01-06), "xv32f07.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:2814853 3' similar to SW:ARL5_RAT P51646 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 5; mRNA sequence", XP002233906, retrieved from EBI Database accession no. AW274697
DATABASE EMBL [online] 30 August 2002 (2002-08-30), "Human novel polynucleotide #89", XP002233907, retrieved from EBI Database accession no. ABK94978
DATABASE EMBL [online] 30 August 2002 (2002-08-30), "Human novel polypeptide #89", XP002233908, retrieved from EBI Database accession no. ABG66754
TANAKA N ET AL: "A NOVEL HUMAN TYROSINE KINASE GENE INDUCIBLE IN T CELLS BY INTERLEUKIN 2", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 324, no. 1, June 1993 (1993-06-01), pages 1 - 5, XP001108908, ISSN: 0014-5793
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