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Title:
ISOTHERMAL NUCLEIC ACID AMPLIFICATION
Document Type and Number:
WIPO Patent Application WO2006087574
Kind Code:
A3
Abstract:
A process of amplifying a nucleic acid template dependent on partial destruction of primer molecules which have extended onto the template molecule followed by strand invasion of the partially destroyed primer template by a replacement primer. The destruction of the primer molecule may be performed by either endonuclease or exonuclease digestion. A signal generation from the amplified products may be obtained by the use of adaptors capable of binding probe molecules as well as the amplified product.

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Inventors:
HOSER MARK JAY (GB)
KURTIS CHRISTIAN (GB)
Application Number:
PCT/GB2006/000578
Publication Date:
October 12, 2006
Filing Date:
February 17, 2006
Export Citation:
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Assignee:
GENEFORM TECHNOLOGIES LTD (GB)
HOSER MARK JAY (GB)
KURTIS CHRISTIAN (GB)
International Classes:
C12Q1/68
Domestic Patent References:
WO1999049081A21999-09-30
WO2001020035A22001-03-22
WO2002036821A22002-05-10
Foreign References:
EP0497272A11992-08-05
US5824517A1998-10-20
US20040058378A12004-03-25
US6399309B12002-06-04
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