Title:
LEARNING SYSTEM, DECISION SYSTEM, AND PREDICTION SYSTEM, AND LEARNING METHOD, DECISION METHOD, AND PREDICTION METHOD
Document Type and Number:
WIPO Patent Application WO/2023/190136
Kind Code:
A1
Abstract:
One embodiment of the present invention provides a learning system, a decision system, and a prediction system, and a learning method, a decision method, and a prediction method. In DNA methylation measurements, there exist a problem of incomplete bisulfite conversion (problem 1), a problem of the occurrence of bias when several different biomarker sequences/genes are amplified together (problem 2), and a problem in that the degree of over-amplification of the non-methylation signal depends on the gene sequence itself and the chemical substance used for the measurement (problem 3). One embodiment of the present invention provides a system and a corresponding method for learning measurement error characteristics in the presence of the three problems and reflecting the learned error characteristics in biomarker selection criteria. Addressing the problem of measurement error characteristic evaluation for DNA methylation in the presence of a combination of problems 1-3 forms a major novelty of the present invention.
Inventors:
SINGH JANMAJAY (JP)
Application Number:
PCT/JP2023/011772
Publication Date:
October 05, 2023
Filing Date:
March 24, 2023
Export Citation:
Assignee:
FUJIFILM CORP (JP)
International Classes:
G16B40/00; C12M1/00; C12M1/34; C12N15/11; C12Q1/6844; C12Q1/6869; G01N33/50; G06N20/00; G16B30/00
Domestic Patent References:
| WO2020008192A2 | 2020-01-09 |
Foreign References:
| JP2021521536A | 2021-08-26 |
Attorney, Agent or Firm:
MATSUURA, Kenzo (JP)
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