Title:
LIGNIN BACTERIOSTATIC AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
Document Type and Number:
WIPO Patent Application WO/2023/040251
Kind Code:
A1
Abstract:
A lignin bacteriostatic agent and a preparation method therefor and an application thereof. 1 g of lignin is suspended in 10-50 mL of a molten salt hydrate according to a ratio; 50-500 μL of an inorganic acid and 0.5 g of phenol are added; a stirring reaction is performed at 90-150°C for 0.5-5 h; after the reaction liquid is cooled, washing with water and drying are performed to obtain depolymerized and phenolated lignin. The bacteriostatic research shows that the bacteriostatic ability of the modified lignin is significantly enhanced after the lignin is depolymerized, phenolated, and modified, and the research shows that the inhibition rates of the modified lignin on Escherichia coli (ATCC 25922) and staphylococcus aureus (ATCC 6538) are respectively 98.89% and 99.99%. In this way, the lignin bacteriostatic agent can replace antibiotics and has huge application potential in the aspect of feed additives.
Inventors:
YANG XIAOHUI (CN)
LI LONG (CN)
JING FEI (CN)
SHANG QIANQIAN (CN)
HU LIHONG (CN)
JIA PUYOU (CN)
BO CAIYING (CN)
ZHOU YONGHONG (CN)
LI LONG (CN)
JING FEI (CN)
SHANG QIANQIAN (CN)
HU LIHONG (CN)
JIA PUYOU (CN)
BO CAIYING (CN)
ZHOU YONGHONG (CN)
Application Number:
PCT/CN2022/086946
Publication Date:
March 23, 2023
Filing Date:
April 15, 2022
Export Citation:
Assignee:
INST CHEMICAL IND FOREST PRODUCTS CAF (CN)
International Classes:
C07G1/00; A01N61/00; C08H7/00
Foreign References:
| CN113861244A | 2021-12-31 | |||
| CN112825961A | 2021-05-25 | |||
| CN109293941A | 2019-02-01 |
Other References:
"Master's Thesis", 1 June 2019, TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY, CN, article XIA, YUE: "Study on Antibacterial Activity of Lignin and Ways to Improve It", pages: 1 - 67, XP009544544, DOI: 10.27359/d.cnki.gtqgu.2019.000614
KAUR RAMANDEEP; UPPAL S. K.; SHARMA POONAM: "Antioxidant and Antibacterial Activities of Sugarcane Bagasse Lignin and Chemically Modified Lignins", SUGAR TECH, SPRINGER INDIA, NEW DELHI, vol. 19, no. 6, 9 February 2017 (2017-02-09), New Delhi , pages 675 - 680, XP036347766, ISSN: 0972-1525, DOI: 10.1007/s12355-017-0513-y
KAUR RAMANDEEP; UPPAL S. K.; SHARMA POONAM: "Antioxidant and Antibacterial Activities of Sugarcane Bagasse Lignin and Chemically Modified Lignins", SUGAR TECH, SPRINGER INDIA, NEW DELHI, vol. 19, no. 6, 9 February 2017 (2017-02-09), New Delhi , pages 675 - 680, XP036347766, ISSN: 0972-1525, DOI: 10.1007/s12355-017-0513-y
Attorney, Agent or Firm:
NANJING JINGWEI PATENT & TRADEMARK AGENCY CO., LTD (CN)
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