Title:
LIPOTEICHOIC ACID-DERIVED GLYCOLIPIDS, AND COMPOSITIONS COMPRISING SAME
Document Type and Number:
WIPO Patent Application WO/2011/025286
Kind Code:
A2
Abstract:
The present invention relates to lipoteichoic acid-derived glycolipids, and to pharmaceutical, food or cosmetic compositions and vaccine adjuvants comprising same. The lipoteichoic acid-derived glycolipids according to the present invention inhibit the production of inflammatory cytokines and thus have anti-inflammatory effects. Therefore, pharmaceutical, food or cosmetic compositions comprising lipoteichoic acid-derived glycolipids of the present invention can be employed for the purpose of preventing and treating inflammatory diseases. The lipoteichoic acid-derived glycolipids of the present invention can be also used as vaccine adjuvants.
Inventors:
CHUNG DAE KYUN (KR)
JANG KYOUNG SOON (KR)
KIM BYUNG GEE (KR)
KIM HAN GEUN (KR)
KIM NA RA (KR)
LEE HEA YOUNG (KR)
JUNG BONG JUN (KR)
KIM TAE RAHK (KR)
JEONG JI HYE (KR)
JANG KYOUNG SOON (KR)
KIM BYUNG GEE (KR)
KIM HAN GEUN (KR)
KIM NA RA (KR)
LEE HEA YOUNG (KR)
JUNG BONG JUN (KR)
KIM TAE RAHK (KR)
JEONG JI HYE (KR)
Application Number:
PCT/KR2010/005755
Publication Date:
March 03, 2011
Filing Date:
August 26, 2010
Export Citation:
Assignee:
RNA INC (KR)
CHUNG DAE KYUN (KR)
JANG KYOUNG SOON (KR)
KIM BYUNG GEE (KR)
KIM HAN GEUN (KR)
KIM NA RA (KR)
LEE HEA YOUNG (KR)
JUNG BONG JUN (KR)
KIM TAE RAHK (KR)
JEONG JI HYE (KR)
CHUNG DAE KYUN (KR)
JANG KYOUNG SOON (KR)
KIM BYUNG GEE (KR)
KIM HAN GEUN (KR)
KIM NA RA (KR)
LEE HEA YOUNG (KR)
JUNG BONG JUN (KR)
KIM TAE RAHK (KR)
JEONG JI HYE (KR)
International Classes:
C07H1/06; C07H11/04; C07H15/04
Domestic Patent References:
| WO1996002555A1 | 1996-02-01 | |||
| WO1996033739A1 | 1996-10-31 |
Foreign References:
| KR20070078107A | 2007-07-31 | |||
| US20040137554A1 | 2004-07-15 |
Other References:
MORATH, S.; A. GEYER ET AL.: "Structure-function relationship of cytokine induction by LTA from Staphylococcus aureus", J. EXP. MED., vol. 193, 2001, pages 393 - 397
DE VOS, W. J.: "Lipoteichoic acid in lactobacilli: D-alanine makes the differences", PROC. NATL. ACAD. SCI. USA, vol. 102, no. 31, 2005, pages 10763 - 4
MOSMANN; COFFMAN, ANN. REV. IMMUNOL., vol. 7, 1989, pages 145 - 173
MORATH, S.; A. GEYER ET AL.: "Structure-function relationship of cytokine induction by LTA from Staphylococcus aureus", J. EXP. MED., vol. 193, no. 3, 2001, pages 393 - 7
DE VOS, W. J.: "Lipoteichoic acid in lactobacilli: D-alanine makes the differences", PROC. NATL. ACAD. SCI. USA, vol. 102, no. 31, 2005, pages 10763 - 4
MOSMANN; COFFMAN, ANN. REV. IMMUNOL., vol. 7, 1989, pages 145 - 173
MORATH, S.; A. GEYER ET AL.: "Structure-function relationship of cytokine induction by LTA from Staphylococcus aureus", J. EXP. MED., vol. 193, no. 3, 2001, pages 393 - 7
Attorney, Agent or Firm:
DANA PATENT LAW FIRM (KR)
특허법인다나 (KR)
특허법인다나 (KR)
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