Title:
MACHINE-LEARNING-BASED PROGNOSIS PREDICTION METHOD AND DEVICE THEREFOR
Document Type and Number:
WIPO Patent Application WO/2022/124724
Kind Code:
A1
Abstract:
A machine-learning-based prognosis prediction method and a device therefor are provided. A prognosis prediction method according to several embodiments of the present disclosure may comprise the steps of: acquiring original data including gene expression data and survival period data about a plurality of patients; pre-processing the acquired original data to configure training data; constructing a prognosis prediction model by using the configured training data; and predicting a prognosis of an examinee by using the prognosis prediction model.
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Inventors:
KIM YI RANG (KR)
LEE YOUNG HEUN (KR)
SIM WOO GWANG (KR)
GU CHANG DAI (KR)
JO JUN HEE (KR)
LEE YOUNG HEUN (KR)
SIM WOO GWANG (KR)
GU CHANG DAI (KR)
JO JUN HEE (KR)
Application Number:
PCT/KR2021/018330
Publication Date:
June 16, 2022
Filing Date:
December 06, 2021
Export Citation:
Assignee:
ONCOCROSS CO LTD (KR)
International Classes:
G16C20/70; G06N3/08; G06N20/00; G16B10/00; G16B40/20; G16C20/30; G16H50/50; G16H50/70
Foreign References:
| KR102299221B1 | 2021-09-07 |
Other References:
CHOI JONGHWAN , PARK SANGHYUN: "A Node2Vec-Based Gene Expression Image Representation Method for Effectively Predicting Cancer Prognosis", KIPS TRANSACTIONS ON SOFTWARE AND DATA ENGINEERING, vol. 8, no. 10, 31 October 2019 (2019-10-31), pages 397 - 402, XP055940611, ISSN: 2287-5905, DOI: 10.3745/ktsde.2019.8.10.397
PARK, CHIHYUN: "Graph-based Semi-Supervised Learning Method for Predicting Prognosis of Cancer.", JOURNAL OF KIISE: COMPUTING PRACTICES AND LETTERS, vol. 19, no. 2, 1 January 2013 (2013-01-01), pages 71 - 76, XP009537382, ISSN: 2093-8020
LI WEI, LI XUE, GAO LI-NA, YOU CHONG-GE: "Integrated Analysis of the Functions and Prognostic Values of RNA Binding Proteins in Lung Squamous Cell Carcinoma", FRONTIERS IN GENETICS, vol. 11, 5 March 2020 (2020-03-05), pages 1 - 13, XP055940619, DOI: 10.3389/fgene.2020.00185
CHEN RICHARD J., LU MING Y., WANG JINGWEN, WILLIAMSON DREW F. K., RODIG SCOTT J., LINDEMAN NEAL I., MAHMOOD FAISAL: "Pathomic Fusion: An Integrated Framework for Fusing Histopathology and Genomic Features for Cancer Diagnosis and Prognosis", IEEE TRANSACTIONS ON MEDICAL IMAGING, vol. 41, no. 4, 1 April 2022 (2022-04-01), USA, pages 757 - 770, XP055940624, ISSN: 0278-0062, DOI: 10.1109/TMI.2020.3021387
DOLEZAL JAMES M., DASH ARIE P., PROCHOWNIK EDWARD V.: "Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers", BMC CANCER, vol. 18, no. 1, 1 December 2018 (2018-12-01), XP055826317, DOI: 10.1186/s12885-018-4178-z
PARK, CHIHYUN: "Graph-based Semi-Supervised Learning Method for Predicting Prognosis of Cancer.", JOURNAL OF KIISE: COMPUTING PRACTICES AND LETTERS, vol. 19, no. 2, 1 January 2013 (2013-01-01), pages 71 - 76, XP009537382, ISSN: 2093-8020
LI WEI, LI XUE, GAO LI-NA, YOU CHONG-GE: "Integrated Analysis of the Functions and Prognostic Values of RNA Binding Proteins in Lung Squamous Cell Carcinoma", FRONTIERS IN GENETICS, vol. 11, 5 March 2020 (2020-03-05), pages 1 - 13, XP055940619, DOI: 10.3389/fgene.2020.00185
CHEN RICHARD J., LU MING Y., WANG JINGWEN, WILLIAMSON DREW F. K., RODIG SCOTT J., LINDEMAN NEAL I., MAHMOOD FAISAL: "Pathomic Fusion: An Integrated Framework for Fusing Histopathology and Genomic Features for Cancer Diagnosis and Prognosis", IEEE TRANSACTIONS ON MEDICAL IMAGING, vol. 41, no. 4, 1 April 2022 (2022-04-01), USA, pages 757 - 770, XP055940624, ISSN: 0278-0062, DOI: 10.1109/TMI.2020.3021387
DOLEZAL JAMES M., DASH ARIE P., PROCHOWNIK EDWARD V.: "Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers", BMC CANCER, vol. 18, no. 1, 1 December 2018 (2018-12-01), XP055826317, DOI: 10.1186/s12885-018-4178-z
Attorney, Agent or Firm:
LIM, Hyung Chul et al. (KR)
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