Title:
MEDICAL DEVICE FOR DELIVERING A THERAPEUTIC SUBSTANCE AND METHOD THEREFOR
Document Type and Number:
WIPO Patent Application WO1998057680
Kind Code:
A3
Abstract:
A device useful for localized delivery of a therapeutic material is provided. The device includes a structure including a porous material; and a water-insoluble salt of a therapeutic material dispersed in the porous material. The water-insoluble salt is formed by contacting an aqueous solution of a therapeutic salt with a heavy metal water-soluble salt dispersed throughout a substantial portion of the porous material. The heavy metal water-soluble salt can be dispersed in the porous material so that the device can be sterilized and the therapeutic material can be loaded in the device in situ, for example, just prior to use. The therapeutic material is preferably a heparin or heparin derivative or analog which renders the material antithrombotic as an implantable or invasive device.
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Inventors:
BERG ERIC P
DINH THOMAS Q
DINH THOMAS Q
Application Number:
PCT/US1998/011145
Publication Date:
March 11, 1999
Filing Date:
June 03, 1998
Export Citation:
Assignee:
MEDTRONIC INC (US)
International Classes:
A61L33/00; (IPC1-7): A61L33/00
Foreign References:
| US3965909A | 1976-06-29 | |||
| GB2268066A | 1994-01-05 |
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