Title:
MEDICAL DEVICE AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OF AN EYE DISEASE OR CONDITION
Document Type and Number:
WIPO Patent Application WO/2019/136512
Kind Code:
A1
Abstract:
A unit dose pharmaceutical composition comprising 2.0 to 8.0 mg of a dry powder of one or more glucocorticoid or mineralocorticoid or a therapeutically active analogue, derivative, homolog, pharmaceutically acceptable salt or conjugate thereof; wherein the composition is comprised in a syringe is disclosed. The composition may also comprise a a sterile, liquid carrier suitable for direct injection into an eye and/or 0.6 to 0.75 % (w/v) of carboxy methyl cellulose (CMC); and 0.015 to 0.04 (w/v) of a surfactant. Also disclosed is a medical device comprising the unit dose pharmaceutical composition, use of the pharmaceutical composition in the treatment of an eye disease or condition or predisposition thereto and a method of treatment of an eye disease or condition or a predisposition thereto in a subject in need thereof including injecting into the eye the pharmaceutical formulation. The injection may comprise an intravitreal and/or suprachoroidal injection.
Inventors:
PENFOLD PHILIP LESLIE (AU)
Application Number:
PCT/AU2019/000002
Publication Date:
July 18, 2019
Filing Date:
January 09, 2019
Export Citation:
Assignee:
EYE CO PTY LTD (AU)
International Classes:
A61K31/573; A61K9/08; A61K9/14; A61P27/02
Domestic Patent References:
| WO2005099715A2 | 2005-10-27 | |||
| WO2015089559A1 | 2015-06-25 | |||
| WO2000002564A1 | 2000-01-20 | |||
| WO2009114521A1 | 2009-09-17 | |||
| WO2005032510A1 | 2005-04-14 | |||
| WO1995003807A1 | 1995-02-09 |
Foreign References:
| US20050101582A1 | 2005-05-12 |
Other References:
"Product Information: KENACORT-A 40 INJECTION (Sterile Triamcinolone Acetonide Suspension USP ) 40 mg in 1 mL", 24 September 2018 (2018-09-24), XP055626606, Retrieved from the Internet [retrieved on 20190124]
Attorney, Agent or Firm:
WARDEN-HUTTON, Paul David (AU)
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