METHOD AND SYSTEM FOR QUANTIFYING BIOMARKER OF A TISSUE

Title:

METHOD AND SYSTEM FOR QUANTIFYING BIOMARKER OF A TISSUE

Document Type and Number:

WIPO Patent Application WO/2019/136513

Kind Code:

A1

Abstract:

The present disclosure relates to a method and a system for quantifying a biomarker of a biological tissue. Two spectral sub-intervals are determined from a plurality of images of the tissue acquired at discrete wavelengths within a main wavelength interval using an imaging sensor in a manner such that the combination of the image data in the at least two spectral sub-intervals are correlated with a clinical variable of interest. The tissue is illuminated using one or more light sources with wavelengths within the at least two spectral sub-intervals. A measurement is of the light reflected by the tissue is acquired using an imaging sensor; and a measure of the biomarker of the tissue is calculated using the acquired measurement. The main wavelength interval is broader than each of the at least two spectral sub-intervals and at least one spectral confounder causing a spectral variability of the acquired image is present in the tissue.

Inventors:

HADOUX XAVIER (AU)
HUI FLORA (AU)
VAN WIJNGAARDEN PETER (AU)
CROWSTON JONATHAN (AU)

Application Number:

PCT/AU2019/000003

Publication Date:

July 18, 2019

Filing Date:

January 11, 2019

Export Citation:

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Assignee:

CENTRE FOR EYE RES AUSTRALIA (AU)

International Classes:

G01J3/28; G06V10/143; G06V10/60; G06V10/58

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