Title:
MEDICAL MATERIAL FOR IN VIVO IMPLANTATION CONTAINING SOFTENING AGENT AND/OR MOISTURIZING AGENT, METHOD FOR CONTROLLING CONTENT OF SOFTENING AGENT AND/OR MOISTURIZING AGENT IN THE MEDICAL MATERIAL, AND METHOD FOR PRODUCING THE MEDICAL MATERIAL FOR IN VIVO IMPLANTATION
Document Type and Number:
WIPO Patent Application WO/2010/106943
Kind Code:
A1
Abstract:
Provided are a medical material for in vivo implantation which causes no retention of an exudate in the surroundings and yet shows a flexibility; a method for controlling the content of a softening agent and/or a moisturizing agent in the medical material; and a method for producing the medical material for in vivo implantation. When a hybrid medical material for in vivo implantation, which comprises a bioabsorbable material containing a softening agent and/or a moisturizing agent and a non-bioabsorbable porous base material, contains a large amount of the softening agent and/or moisturizing agent, retention of an exudate occurs in the surroundings of the medical material. It is found out that this phenomenon is a side effect of the softening agent and/or moisturizing agent. To prevent this side effect, a medical material for in vivo implantation in which the content of a softening agent and/or a moisturizing agent is controlled to less than 20 wt%; a method for controlling said content; and a method for producing the medical material for in vivo implantation are provided.
Inventors:
NOISHIKI YASUHARU (JP)
Application Number:
PCT/JP2010/053936
Publication Date:
September 23, 2010
Filing Date:
March 03, 2010
Export Citation:
Assignee:
NICEM LTD (JP)
NOISHIKI YASUHARU (JP)
NOISHIKI YASUHARU (JP)
International Classes:
A61L27/00
Foreign References:
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| JPH06285150A | 1994-10-11 | |||
| JP2005124959A | 2005-05-19 | |||
| JPS6434360U | 1989-03-02 | |||
| JPH11164881A | 1999-06-22 | |||
| JPH08294530A | 1996-11-12 | |||
| US4842575A | 1989-06-27 | |||
| US5108424A | 1992-04-28 | |||
| US5197977A | 1993-03-30 | |||
| US5851229A | 1998-12-22 | |||
| US6177609B1 | 2001-01-23 | |||
| US6299639B1 | 2001-10-09 | |||
| US5584875A | 1996-12-17 | |||
| US6368347B1 | 2002-04-09 | |||
| US6670096B2 | 2003-12-30 | |||
| US4990158A | 1991-02-05 | |||
| JP2004313310A | 2004-11-11 | |||
| US6177609B1 | 2001-01-23 | |||
| US6299693B1 | 2001-10-09 | |||
| JP2005124959A | 2005-05-19 |
Other References:
CHEST SURGICAL, vol. 46, 1993, pages 1093 - 98
ASAIO TRANS., vol. 34, July 1988 (1988-07-01), pages 789 - 93
J SURG RES., vol. 95, February 2001 (2001-02-01), pages 152 - 60
J BIOMATER., vol. 10, April 1996 (1996-04-01), pages 309 - 29
J BIOMATER. SCI POLYM ED., vol. 14, 2003, pages 1057 - 75
J ARTIF ORGANS, vol. 25, August 2002 (2002-08-01), pages 777 - 82
J ARTIF ORGANS, vol. 22, December 1999 (1999-12-01), pages 843 - 53
See also references of EP 2417989A4
ASAIO TRANS., vol. 34, July 1988 (1988-07-01), pages 789 - 93
J SURG RES., vol. 95, February 2001 (2001-02-01), pages 152 - 60
J BIOMATER., vol. 10, April 1996 (1996-04-01), pages 309 - 29
J BIOMATER. SCI POLYM ED., vol. 14, 2003, pages 1057 - 75
J ARTIF ORGANS, vol. 25, August 2002 (2002-08-01), pages 777 - 82
J ARTIF ORGANS, vol. 22, December 1999 (1999-12-01), pages 843 - 53
See also references of EP 2417989A4
Attorney, Agent or Firm:
TANAKA Hiroshi et al. (JP)
Hiroshi Tanaka (JP)
Hiroshi Tanaka (JP)
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