Title:
MEDICAMENT FOR PREVENTING OR TREATING FATTY LIVER
Document Type and Number:
WIPO Patent Application WO/2006/022237
Kind Code:
A1
Abstract:
Disclosed is a medicament for preventing or treating fatty liver. Specifically disclosed is a pharmaceutical composition characterized by containing a compound represented by the general formula (I): (wherein R1 and R2 respectively represent a hydrogen or a lower alkyl; R3, R4, R5 and R6 respectively represent a hydrogen, a halogen, a lower alkyl or a lower alkoxy; R7 and R8 respectively represent a hydrogen, a halogen, a lower alkyl, a halogenated lower alkyl, a lower alkoxy, a cycloalkyl, an aryl, a heteroaryl, a cyano, a hydroxyl, a lower acyl, a carboxy or the like; and R9 represents -C(O)-R10, -A1-C(O)-R10, -O-A2-C(O)-R10 or a tetrazole-5-yl group), a prodrug thereof, or a pharmacologically acceptable salt of them as an active constituent. Such a pharmaceutical composition is extremely suitable as a medicament for preventing or treating fatty liver.
Inventors:
TAKEDA HIROO (JP)
AKAHANE SATOSHI (JP)
AKAHANE SATOSHI (JP)
Application Number:
PCT/JP2005/015234
Publication Date:
March 02, 2006
Filing Date:
August 23, 2005
Export Citation:
Assignee:
KISSEI PHARMACEUTICAL (JP)
TAKEDA HIROO (JP)
AKAHANE SATOSHI (JP)
TAKEDA HIROO (JP)
AKAHANE SATOSHI (JP)
International Classes:
A61K31/195; A61K31/05; A61K31/24; A61K31/343; A61K31/606; A61P1/16; C07C217/18; C07C217/20; C07C323/62; C07D307/79
Domestic Patent References:
| WO2004072016A1 | 2004-08-26 | |||
| WO2005040093A1 | 2005-05-06 | |||
| WO2005061433A2 | 2005-07-07 |
Foreign References:
| US20030212063A1 | 2003-11-13 |
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