Title:
MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER
Document Type and Number:
WIPO Patent Application WO/2024/048541
Kind Code:
A1
Abstract:
This medicament, which contains, together or separately in combination with a CDK inhibitor, an antibody or a fragment thereof having an immunological reactivity with a CAPRIN-1 protein, is useful for treating and/or preventing cancer.
Inventors:
WASAI UKEI (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
Application Number:
PCT/JP2023/031072
Publication Date:
March 07, 2024
Filing Date:
August 29, 2023
Export Citation:
Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K39/395; A61K31/506; A61K31/519; A61K45/00; A61P35/00; A61P35/02; A61P43/00; C07K16/28; C12N15/13; C12P21/08
Domestic Patent References:
| WO2019189780A1 | 2019-10-03 | |||
| WO2011096535A1 | 2011-08-11 |
Foreign References:
| JP2022534889A | 2022-08-04 |
Other References:
ETTL TOBIAS, SCHULZ DANIELA, BAUER RICHARD: "The Renaissance of Cyclin Dependent Kinase Inhibitors", CANCERS, CH, vol. 14, no. 2, 7 January 2022 (2022-01-07), CH , pages 293, XP093145786, ISSN: 2072-6694, DOI: 10.3390/cancers14020293
FRANCO YESENIA L.; RAMAKRISHNAN VIDYA; VAIDYA TANAYA R.; MODY HARDIK; PEREZ LUIS; AIT-OUDHIA SIHEM: "A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer", JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, PLENUM PUBLISHING, US, vol. 48, no. 2, 3 January 2021 (2021-01-03), US , pages 273 - 293, XP037430252, ISSN: 1567-567X, DOI: 10.1007/s10928-020-09732-x
STEINEBACH CHRISTIAN, NG YUEN LAM DORA, SOSIČ IZIDOR, LEE CHIH-SHIA, CHEN SIRUI, LINDNER STEFANIE, VU LAN PHUONG, BRICELJ ALEŠA, H: "Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders", CHEMICAL SCIENCE, ROYAL SOCIETY OF CHEMISTRY, UNITED KINGDOM, vol. 11, no. 13, 1 April 2020 (2020-04-01), United Kingdom , pages 3474 - 3486, XP055858556, ISSN: 2041-6520, DOI: 10.1039/D0SC00167H
YANG TE, HUANG LONG, QIN HAIDE, MAI SHIJUAN: "STRESS granule-associated RNA-binding protein CAPRIN1 drives cancer progression and regulates treatment response in nasopharyngeal carcinoma", MEDICAL ONCOLOGY, SPRINGER-VERLAG, NEW YORK, vol. 40, no. 1, 14 December 2022 (2022-12-14), New York , pages 47, XP093143451, ISSN: 1559-131X, DOI: 10.1007/s12032-022-01910-w
FRANCO YESENIA L.; RAMAKRISHNAN VIDYA; VAIDYA TANAYA R.; MODY HARDIK; PEREZ LUIS; AIT-OUDHIA SIHEM: "A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer", JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS, PLENUM PUBLISHING, US, vol. 48, no. 2, 3 January 2021 (2021-01-03), US , pages 273 - 293, XP037430252, ISSN: 1567-567X, DOI: 10.1007/s10928-020-09732-x
STEINEBACH CHRISTIAN, NG YUEN LAM DORA, SOSIČ IZIDOR, LEE CHIH-SHIA, CHEN SIRUI, LINDNER STEFANIE, VU LAN PHUONG, BRICELJ ALEŠA, H: "Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders", CHEMICAL SCIENCE, ROYAL SOCIETY OF CHEMISTRY, UNITED KINGDOM, vol. 11, no. 13, 1 April 2020 (2020-04-01), United Kingdom , pages 3474 - 3486, XP055858556, ISSN: 2041-6520, DOI: 10.1039/D0SC00167H
YANG TE, HUANG LONG, QIN HAIDE, MAI SHIJUAN: "STRESS granule-associated RNA-binding protein CAPRIN1 drives cancer progression and regulates treatment response in nasopharyngeal carcinoma", MEDICAL ONCOLOGY, SPRINGER-VERLAG, NEW YORK, vol. 40, no. 1, 14 December 2022 (2022-12-14), New York , pages 47, XP093143451, ISSN: 1559-131X, DOI: 10.1007/s12032-022-01910-w
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