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Title:
MEDICAMENT FOR TREATMENT AND/OR PREVENTION OF CANCER
Document Type and Number:
WIPO Patent Application WO/2024/048542
Kind Code:
A1
Abstract:
This medicament, which contains, together or separately in combination with a PARP inhibitor, an antibody or a fragment thereof having an immunological reactivity with a CAPRIN-1 protein, is useful for treating and/or preventing cancer.

Inventors:
WASAI UKEI (JP)
OKANO FUMIYOSHI (JP)
SAITO TAKANORI (JP)
Application Number:
PCT/JP2023/031077
Publication Date:
March 07, 2024
Filing Date:
August 29, 2023
Export Citation:
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Assignee:
TORAY INDUSTRIES (JP)
International Classes:
A61K45/00; A61K31/501; A61K39/395; A61P35/00; A61P35/02; A61P43/00; C07K16/28; C12N15/13; C12P21/08
Domestic Patent References:
WO2019189780A12019-10-03
WO2011096535A12011-08-11
Foreign References:
JP2018534321A2018-11-22
JP2021535215A2021-12-16
Other References:
MILLER MARINA, DANIEL FALCON, CHELSEA GREGORY-GOFF, ICHIKO KINJYO, SARAH ADAM: "419 - Poster Session Oophorectomy significantly impacts response to immune therapy regimens in preclinical models of ovarian cancer ", vol. 162, no. Suppl 1, 1 January 2021 (2021-01-01), pages S220, XP093143447
矢内原臨他, 卵巣癌におけるHRDとPARP阻害薬の効果 今後期待されるPARP阻害薬の臨床試験, 産婦人科の実際, 2021, vol. 70, no. 5 , pp. 555-560
OZAKI, YUKINORI: "Checkpoint blockade strategies in hormone receptor-positive and/or HER2-positive breast cancer", CLINICAL ONCOLOGY, JP, vol. 24, no. 2, 1 January 2019 (2019-01-01), JP , pages 137 - 142, XP009547711, ISSN: 1881-6568
YANG TE, HUANG LONG, QIN HAIDE, MAI SHIJUAN: "STRESS granule-associated RNA-binding protein CAPRIN1 drives cancer progression and regulates treatment response in nasopharyngeal carcinoma", MEDICAL ONCOLOGY, SPRINGER-VERLAG, NEW YORK, vol. 40, no. 1, 14 December 2022 (2022-12-14), New York , pages 47, XP093143451, ISSN: 1559-131X, DOI: 10.1007/s12032-022-01910-w
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