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Title:
MEDICINAL COMPOSITION FOR TREATING CANCER
Document Type and Number:
WIPO Patent Application WO/2016/024369
Kind Code:
A1
Abstract:
Provided is a liquid medicinal composition formed by containing: (A) pemetrexed, a pharmaceutically acceptable salt or solvate thereof; (B) cysteine, a pharmaceutically acceptable salt or solvate thereof; and (C) a chelating agent. The liquid medicinal composition containing pemetrexed according to the present invention exhibits a suppressed increase of related substances and also suppressed coloring even after long-term storage, so that the composition may be appropriately applied to the treatment of, for example, malignant pleural mesothelioma and non-small cell lung cancer.

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Inventors:
MIURA YOSHIYUKI
MURATA MITSUTAKA
NISHIDA TAKASHI
Application Number:
PCT/JP2014/082226
Publication Date:
February 18, 2016
Filing Date:
December 05, 2014
Export Citation:
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Assignee:
TEVA PHARMA JAPAN INC (JP)
International Classes:
A61K31/519; A61K9/08; A61K47/18; A61K47/20; A61P35/00
Foreign References:
JP2014237607A2014-12-18
JP2013540104A2013-10-31
JPS6440493A1989-02-10
JPS63310815A1988-12-19
JP2003535827A2003-12-02
JP2010502565A2010-01-28
JP2003521518A2003-07-15
Attorney, Agent or Firm:
HOSODA, YOSHINORI (JP)
Yoshinori Hosoda (JP)
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