Title:
MESOTHELIN (MSLN) ANTIBODY AND USE THEREOF
Document Type and Number:
WIPO Patent Application WO/2011/074621
Kind Code:
A1
Abstract:
Disclosed is a tumor cell imaging agent containing anti-mesothelin antibody. As a result of the research of the inventors focusing on the aforementioned mesothelin, cultured cells derived from cancer cells inoculated subcutaneously into mice were imaged using labeled mesothelin antibodies.
Inventors:
MATSUURA EIJI (JP)
KUMON HIROMI (JP)
KISHI YOSHIRO (JP)
FUJII YOSHIHIRO (JP)
KUMON HIROMI (JP)
KISHI YOSHIRO (JP)
FUJII YOSHIHIRO (JP)
Application Number:
PCT/JP2010/072608
Publication Date:
June 23, 2011
Filing Date:
December 16, 2010
Export Citation:
Assignee:
MEDICAL & BIOL LAB CO LTD (JP)
UNIV OKAYAMA NAT UNIV CORP (JP)
MATSUURA EIJI (JP)
KUMON HIROMI (JP)
KISHI YOSHIRO (JP)
FUJII YOSHIHIRO (JP)
UNIV OKAYAMA NAT UNIV CORP (JP)
MATSUURA EIJI (JP)
KUMON HIROMI (JP)
KISHI YOSHIRO (JP)
FUJII YOSHIHIRO (JP)
International Classes:
A61K49/00; A61B5/055; G01R33/28
Foreign References:
| JP2007071849A | 2007-03-22 |
Other References:
ATSUSHI TSUJI ET AL.: "Shuyo Kenkyu Jo no Yuyosei", NIRS-M, March 2009 (2009-03-01), pages 11 - 12
HASSAN,R. ET AL.: "lndium-labeled monoclonal antibody Kl: biodistribution study in nude mice bearing a human carcinoma xenograft expressing mesothelin", INT J CANCER, vol. 80, no. 4, 1999, pages 559 - 63
IWAHORI,K. ET AL.: "Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin", LUNG CANCER, vol. 62, no. 1, 2008, pages 45 - 54
HASSAN,R. ET AL.: "Mesothelin targeted cancer immunotherapy", EUR J CANCER, vol. 44, no. 1, 2008, pages 46 - 53
HASSAN,R. ET AL.: "lndium-labeled monoclonal antibody Kl: biodistribution study in nude mice bearing a human carcinoma xenograft expressing mesothelin", INT J CANCER, vol. 80, no. 4, 1999, pages 559 - 63
IWAHORI,K. ET AL.: "Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: evaluation in comparison with mesothelin", LUNG CANCER, vol. 62, no. 1, 2008, pages 45 - 54
HASSAN,R. ET AL.: "Mesothelin targeted cancer immunotherapy", EUR J CANCER, vol. 44, no. 1, 2008, pages 46 - 53
Attorney, Agent or Firm:
SHIMIZU, Hatsushi et al. (JP)
Spring water Original aim (JP)
Spring water Original aim (JP)
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