Title:
METHOD FOR ANALYZING NEURAL TRANSMISSION OF BASAL GANGLIA NEURAL CIRCUITS
Document Type and Number:
WIPO Patent Application WO/2011/135632
Kind Code:
A1
Abstract:
Disclosed are a method for analyzing the neural transmission of basil ganglia neural circuits and a method for searching for substances that affect the neural transmission of the basil ganglia neural circuits. By using a transgenic nonhuman animal in which direct pathways and/or indirect pathways from among the basil ganglia neural circuits have been blocked, it is possible to analyze the neural transmission of the basil ganglia neural circuits and search for substances that affect the neural transmission of the basil ganglia neural circuits.
Inventors:
HIKIDA TAKATOSHI (JP)
NAKANISHI SHIGETADA (JP)
NAKANISHI SHIGETADA (JP)
Application Number:
PCT/JP2010/003089
Publication Date:
November 03, 2011
Filing Date:
April 30, 2010
Export Citation:
Assignee:
OSAKA BIOSCIENCE INST (JP)
HIKIDA TAKATOSHI (JP)
NAKANISHI SHIGETADA (JP)
HIKIDA TAKATOSHI (JP)
NAKANISHI SHIGETADA (JP)
International Classes:
A01K67/027; C12N15/00; C12Q1/68
Other References:
TAKATOSHI HIKITA: "132. Kagyakuteki Shinkei Dentatsu Soshiho ni yoru Daino Kiteikaku Kairo no Seigyo Kiko no Kaimei", RESEARCH REPORTS OF UEHARA MEMORIAL FOUNDATION, vol. 23, 22 December 2009 (2009-12-22), pages 1 - 5
WADA, N. ET AL.: "Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104, no. 42, 16 October 2007 (2007-10-16), pages 16690 - 16695
SATOSHI KANEKO ET AL.: "Senjotai Choline Sadosei Interneuron ni yoru Kiteikaku Shinkei Kairo no Kasosei no Kaiseki", CLINICAL NEUROLOGY, vol. 41, no. 11, 1 November 2001 (2001-11-01), pages 860
MINETO YOKOI: "Senjotai CREB Joho Dentatsukei ni Chumoku shita Ko Yakubutsu Izonshoyaku no Kaihatsu", ANNUAL REPORT OF PHARMACOPSYCHIATRY RESEARCH, 25 March 2006 (2006-03-25), pages 233 - 236
WADA, N. ET AL.: "Conditioned eyeblink learning is formed and stored without cerebellar granule cell transmission", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104, no. 42, 16 October 2007 (2007-10-16), pages 16690 - 16695
SATOSHI KANEKO ET AL.: "Senjotai Choline Sadosei Interneuron ni yoru Kiteikaku Shinkei Kairo no Kasosei no Kaiseki", CLINICAL NEUROLOGY, vol. 41, no. 11, 1 November 2001 (2001-11-01), pages 860
MINETO YOKOI: "Senjotai CREB Joho Dentatsukei ni Chumoku shita Ko Yakubutsu Izonshoyaku no Kaihatsu", ANNUAL REPORT OF PHARMACOPSYCHIATRY RESEARCH, 25 March 2006 (2006-03-25), pages 233 - 236
Attorney, Agent or Firm:
SHOJI, Takashi et al. (JP)
Takashi Shoji (JP)
Takashi Shoji (JP)
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Claims: