Title:
METHOD AND APPARTUS FOR OPTIMIZING CARDIAC RESYNCHRONIZATION THERAPY BASED ON LEFT VENTRICULAR ACCELERATION
Document Type and Number:
WIPO Patent Application WO2004078257
Kind Code:
B1
Abstract:
A system and method for monitoring left ventricular cardiac contractility and for optimizing a cardiac therapy based on left ventricular lateral wall acceleration (LVA) are provided. The system includes an implantable or external cardiac stimulation device in association with a set of leads including a left ventricular epicardial or coronary sinus lead equipped with an acceleration sensor. The device receives and processes acceleration sensor signals to determine a signal characteristic indicative of LVA during isovolumic contraction. A therapy optimization method evaluates the LVA during varying therapy settings and selects the setting(s) that correspond to a maximum LVA during isovolumic contraction. In one embodiment, the optimal inter-ventricular pacing interval for use in cardiac resynchronization therapy is determined as the interval corresponding to the highest amplitude of the first LVA peak during isovolumic contraction.
Inventors:
CHINCHOY EDWARD (US)
Application Number:
PCT/US2004/004902
Publication Date:
November 04, 2004
Filing Date:
February 19, 2004
Export Citation:
Assignee:
MEDTRONIC INC (US)
CHINCHOY EDWARD (US)
CHINCHOY EDWARD (US)
International Classes:
A61N1/362; A61N1/365; A61N1/368; (IPC1-7): A61N1/362
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