Title:
METHOD FOR ASSESSING COAGULATION INHIBITION ACTIVITY OR COAGULATION PROMOTION ACTIVITY AGAINST COAGULATIVE PROTEIN
Document Type and Number:
WIPO Patent Application WO/2024/071361
Kind Code:
A1
Abstract:
The purpose of the present invention is to provide a screening method for a coagulation inhibition activity substance or a coagulation promotion activity substance for a coagulative protein. Specifically, the present invention pertains to a method that is for assessing the coagulation inhibition activity or coagulation promotion activity, of a test substance, against a coagulative protein, and that comprises: a step for culturing cells in the presence of the test substance and the coagulative protein that has a label; and a step for quantifying, by using the label as an indicator, the coagulative protein that have coagulated and/or been deposited on the surfaces of the cells and/or in the cells in the cell culture.
Inventors:
NISHISHITA NAOKI (JP)
Application Number:
PCT/JP2023/035564
Publication Date:
April 04, 2024
Filing Date:
September 22, 2023
Export Citation:
Assignee:
KANEKA CORP (JP)
International Classes:
G01N33/50; C12N5/079; C12Q1/02; G01N33/15; G01N33/53; G01N33/536
Domestic Patent References:
| WO2020138265A1 | 2020-07-02 | |||
| WO2006038729A1 | 2006-04-13 |
Foreign References:
| JP2008530999A | 2008-08-14 | |||
| JP2020188700A | 2020-11-26 | |||
| JP2001501972A | 2001-02-13 | |||
| JP2004170387A | 2004-06-17 | |||
| JP2001515044A | 2001-09-18 | |||
| JP2017007990A | 2017-01-12 | |||
| JP2013234167A | 2013-11-21 | |||
| JP2004536600A | 2004-12-09 | |||
| JP2008521937A | 2008-06-26 | |||
| JP2012515214A | 2012-07-05 |
Attorney, Agent or Firm:
HIRAKI & ASSOCIATES (JP)
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